1493772-41-0Relevant academic research and scientific papers
Sterically Hindered Amination of Aryl Chlorides Catalyzed by a New Carbazolyl-Derived P,N-Ligand-Composed Palladium Complex
Choy, Pui Ying,Kwong, Fuk Yee,Lai, Wing In,Leung, Man Pan
, p. 2678 - 2686 (2019)
A family of 2-(9 H -carbazol-9-yl)phenyl-based phosphine ligands were synthesized and their efficacy in promoting the steric hindered Buchwald-Hartwig amination was evaluated. In the presence of Pd(OAc) 2 (0.03-1.0 molpercent) associated with t
SYNTHESES OF N-HETEROCYCLIC CARBENES AND INTERMEDIATES THEREFOR
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Page/Page column 44; 45, (2014/07/23)
A method of preparing a 2,6 disubstituted anilines includes, reacting a 2-amino isophtha!ic acid diester with sufficient Grignard reagent R2CH2MgX to form the corresponding diol product, dehydrating the diol product to the corresponding dialkene; and hydrogenating the diol product to form the corresponding aniline. The 2,6 disubstituted anilines can be used to produce N-Heterocyciic Carbenes (NHCs). The NHCs can find application in various fields such as organic synthesis, catalysis and macromolecular chemistry. Palladium catalysts containing the NHCs are also described.
Effect of electronic enrichment of NHCs on the catalytic activity of [Pd(NHC)(acac)Cl] in Buchwald-Hartwig coupling
Le Duc, Gaetan,Meiries, Sebastien,Nolan, Steven P.
supporting information, p. 7547 - 7551 (2014/04/03)
A series of [Pd(NHC)(acac)Cl] (NHC = N-heterocyclic carbene) complexes have been synthesized and characterized to investigate the electronic and steric effects of NHC ligands in catalysis. Their reactivity in Buchwald-Hartwig coupling has been explored an
