149398-49-2

Upstream product

• 149494-46-2 [(2R)-8-methoxy-3,4-dihydro-2H-chromen-2-yl]methanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 913824-84-7 8-methoxy-2H-1-benzopyran-2-methanol 4-methylbenzenesulfonate 

Downstream Products

• 913827-30-2 toluene-4-sulfonic acid 8-hydroxy-chroman-2-yl-methyl ester 

Relevant academic research and scientific papers

CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF

Compounds of formula I or pharmaceutically acceptable salts thereof are provided: wherein each of R1, R2, R3, R4, y, m, n, and Ar are as defined, and described in classes and subclasses herein, which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions containing the compounds, can be used to treat a variety of central nervous system disorders such as schizophrenia.

Antidepressant chroman and chromene derivatives of 3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole

Compounds of the formula useful for the treatment of depression and other diseases such as obsessive compulsive disorder, panic attacks, generalized anxiety disorder, social anxiety disorder, sexual dysfunction, eating disorders, obesity, addictive disord