14944-28-6

Basic information

• Product Name: 1-methyl-1,2,3,4-tetrahydronaphthalen-1-ol
• Synonyms: 1-Methyl-1,2,3,4-tetrahydro-1-naphthalenol; 1-naphthalenol, 1,2,3,4-tetrahydro-1-methyl-
• CAS NO: 14944-28-6
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.2283
• Mol File: 14944-28-6.mol
• Article Data: 27

Chemical Properties

• Boiling Point: 270.1°C at 760 mmHg
• Flash Point: 102°C
• Density: 1.069g/cm³
• Vapor Pressure: 0.00343mmHg at 25°C
• Refractive Index: 1.562
• CAS DataBase Reference: 1-methyl-1,2,3,4-tetrahydronaphthalen-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-1,2,3,4-tetrahydronaphthalen-1-ol(14944-28-6)
• EPA Substance Registry System: 1-methyl-1,2,3,4-tetrahydronaphthalen-1-ol(14944-28-6)

Safety Data

• Hazardous Substances Data: 14944-28-6(Hazardous Substances Data)

Usage

Type of compound

Alcohol

Derived from

Tetrahydronaphthalene (a bicyclic hydrocarbon)

Usage

Production of fragrances and flavors

Common applications

Perfumes and cosmetic products

Scent

Slightly floral, woody

Benefits in fragrances

Adds depth and complexity

Potential medicinal properties

Anti-inflammatory and antimicrobial agent

Industries of application

Fragrance, cosmetic, and pharmaceutical (potentially)

Upstream product

• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 1058726-78-5 5-(2-fluorophenyl)pentan-2-one 
• 925-90-6 ethylmagnesium bromide 
• 917-54-4 methyllithium 
• 75-16-1 methylmagnesium bromide 
• 676-58-4 methylmagnesium chloride 
• 917-64-6 methyl magnesium iodide 
• 74-88-4 methyl iodide 
• 18006-13-8 methyltriisopropoxytitanium(IV) 

Downstream Products

• 123973-90-0 5-(o-hydroxyphenyl)-2-pentanone 
• 1444403-84-2 (E)-methyl 5-(2-acetylphenyl)pent-2-enoate 
• 99865-14-2 3-(2-acetylphenyl)propanal 
• 51086-31-8 1-methyl-1,2,3,4-tetrahydronaphthalene-r-1,c-2-diol 
• 4024-14-0 1-methyl-2-tetralone 
• 99964-59-7 1-methyl-1,2,3,4-tetrahydro-1-naphthalenyl hydroperoxide 
• 66405-16-1 3-(2-acetylphenyl)propanoic acid 
• 90-12-0 1-Methylnaphthalene 

Relevant articles and documents

Optically active tertiary alcohols by biocatalysis

Initially, chemoenzymatic route to optically active aromatic ring-fused cyclic tertiary alcohols (S)-(–)-1-methyl-1,2,3,4-tetrahydronaphthalen-1-ol-(–)-1b, (S)-(+)-1-methyl-2,3-dihydro-1H-inden-1-ol-(+)-1a has been reported.[9] CAL-A (lipase-A from Candida antarctica) was found the best biocatalyst for 1b, CAL-A cross linked enzyme aggregate (CLEA) for 1a, with ee values of 20 and 45% and the esters 2b and 2a with ee values 99 and 71%. Then, cyclopent-2-ene anchored tertiary allyl 1a′, homoallyl 1b′ and homopropargyl 1c alcohols have been enzymaticly resolved in a high ee (up to 90%) with 44, 40, and 43% chemical yield, respectively, cyclohex-2-ene anchored tertiary allyl 3a, homoallyl 3b, and homopropargyl 3c alcohols in high ee (up to 97%) too with 42, 45, and 49% chemical yield in turn. Chiral dienes yield the spirocyclic dihydropyrans through ring-closing methathesis with 74 and 78% chemical yields with 90 and 97% ee. Chiral enynes afford the cyclopentenone pyrans through Pauson–Khand reaction with 80 and 81% chemical yields as single diastereomers as reported subsequently.[1a]

Dynamic kinetic resolution of a tertiary alcohol

In spite of the tremendous success of dynamic kinetic resolutions for a broad range of compound classes, tertiary alcohols and their corresponding esters have still remained as one of the most challenging substrates for this type of process. This is due t

COMPOUND, RESIN, RESIST COMPOSITION, AND METHOD FOR PRODUCING RESIST PATTERN

PROBLEM TO BE SOLVED: To provide a resin and a resist composition capable of producing a resist pattern with good LER. SOLUTION: Provided is a compound represented by formula (I) [R1 is H or methyl; R2 is a C1-6 alkyl; L1