14944-99-1

Basic information

• Product Name: 3-ethyl-2-hydroxy-1-methylquinolin-4(1H)-one
• CAS NO: 14944-99-1
• Molecular Formula: C₁₂H₁₃NO₂
• Molecular Weight: 203.2371
• Mol File: 14944-99-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 317.3°C at 760 mmHg
• Flash Point: 145.7°C
• Density: 1.212g/cm³
• Vapor Pressure: 0.000163mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 3-ethyl-2-hydroxy-1-methylquinolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ethyl-2-hydroxy-1-methylquinolin-4(1H)-one(14944-99-1)
• EPA Substance Registry System: 3-ethyl-2-hydroxy-1-methylquinolin-4(1H)-one(14944-99-1)

Safety Data

• Hazardous Substances Data: 14944-99-1(Hazardous Substances Data)

Upstream product

• 106875-06-3 4-Amino-3-ethyl-1-methyl-2(1H)-chinolon 
• 133-13-1 ethyl diethyl malonate 
• 100-61-8 N-methylaniline 
• 1399323-87-5 3-ethyl-1,2,3,4-tetrahydro-1-methyl-2,4-dioxoquinolin-3-yl thiocyanate 
• 110254-72-3 4-Chlor-3-ethyl-1-methyl-2(1H)-chinolon 
• 54289-76-8 3-acetyl-4-hydroxy-1-methyl-2(1H)-quinolone 

Downstream Products

• 110216-96-1 3-Ethyl-1-methyl-4-tosyloxy-2(1H)-chinolon 
• 110229-52-2 4-Benzylamino-3-ethyl-1-methyl-2(1H)-chinolon 

Relevant articles and documents

Oxidative ring opening of 3-hydroxyquinoline-2,4(1H,3H)-diones into N-(α-ketoacyl)anthranilic acids Dedicated to Professor Slovenko Polanc on his 65th birthday

N-(α-Ketoacyl)anthranilic acids were prepared by oxidative ring opening of 3-hydroxyquinoline-2,4(1H,3H)-diones by using paraperiodic acid (H5IO6) or sodium periodate (NaIO4). The optimisation of the reaction conditions is

A simple and effective method for the reduction of acyl substituted heterocyclic 1,3-dicarbonyl compounds to alkyl derivatives by zinc - acetic acid - hydrochloric acid

3-Acyl-4-hydroxy-2(1H)-quinolones (1a-k) were reduced in good yields (66-97%) to 3-alkyl-4-hydroxy-2(1H)-quinolinones (2a-k) using zinc powder (particle size 〈45 μm) in acetic acid/hydrochloric acid. This method could be transformed to 3-acetyl-4-hydroxy-