1494644-95-9

Basic information

• Product Name: [3-(4-chlorophenyl)prop-2-yn-1-yl](3-phenylprop-2-en-1-yl)morpholinium bromide
• Synonyms: [3-(4-chlorophenyl)prop-2-yn-1-yl](3-phenylprop-2-en-1-yl)morpholinium bromide
• CAS NO: 1494644-95-9
• Molecular Weight: 432.788
• Mol File: 1494644-95-9.mol

Chemical Properties

• CAS DataBase Reference: [3-(4-chlorophenyl)prop-2-yn-1-yl](3-phenylprop-2-en-1-yl)morpholinium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(4-chlorophenyl)prop-2-yn-1-yl](3-phenylprop-2-en-1-yl)morpholinium bromide(1494644-95-9)
• EPA Substance Registry System: [3-(4-chlorophenyl)prop-2-yn-1-yl](3-phenylprop-2-en-1-yl)morpholinium bromide(1494644-95-9)

Safety Data

• Hazardous Substances Data: 1494644-95-9(Hazardous Substances Data)

Upstream product

• 342627-03-6 4-(3-(4-chlorophenyl)prop-2-ynyl)morpholine 
• 4392-24-9 3-bromo-1-phenyl-1-propenyl bromide 

Downstream Products

• 1494645-10-1 6-chloro-4-phenylspiro-3a,4-dihydrobenzo[f]isoindoline-2,4'-morpholinium bromide 

Relevant articles and documents

Base-catalyzed intramolecular Diels-Alder cyclization of dialkyl(3-arylprop-2-yn-1-yl)-(3-phenylprop-2-en-1-yl)ammonium bromides in aqueous solution

Dialkyl(3-arylprop-2-yn-1-yl)(3-phenylprop-2-en-1-yl)ammonium bromides, in contrast to their allyl analogs containing a 3-arylprop-2-en-1-yl group, undergo cyclization in aqueous solution in the presence of base upon prior heating to give potentially biologically active 2,2-dialkyl-6-chloro-4-phenyl-3a,4- dihydrobenzo[f]isoindolinium bromides in almost quantitative yield. Heat is released in the course of these reactions. We found that the introduction of a phenyl group at position 3 of the allyl fragment facilitates the cyclization. This is the first report of a base-catalyzed intramolecular cyclization of allyl analogs of dialkyl(3-arylprop-2-yn-1-yl)ammonium salts.