149488-17-5 Usage
Description
Trovirdine, also known as trovirdine maleate, is an antiviral drug that belongs to the non-nucleoside reverse transcriptase inhibitor (NNRTI) class. It is specifically designed to inhibit the replication of the human immunodeficiency virus type 1 (HIV-1) by targeting its reverse transcriptase enzyme. Trovirdine demonstrates high specificity and potency against HIV-1, making it a valuable addition to the arsenal of antiretroviral medications.
Source:
Trovirdine is synthesized through a series of chemical reactions involving various starting materials and reagents. The exact process may vary depending on the specific synthesis route employed by different manufacturers.
Production Methods:
The production of trovirdine typically involves a multi-step synthesis process, which may include the formation of key intermediates, subsequent functional group transformations, and final purification steps to obtain the desired compound with the required purity and potency.
Uses
Used in Pharmaceutical Industry:
Trovirdine is used as an antiviral agent for the treatment of HIV-1 infection. It works by inhibiting the HIV-1 reverse transcriptase enzyme (RT) with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA) and dGTP as a substrate. This inhibition prevents the conversion of viral RNA into DNA, thereby suppressing the replication of the virus and slowing down the progression of the disease in infected individuals.
Additionally, trovirdine can be used in combination with other antiretroviral drugs as part of a highly active antiretroviral therapy (HAART) regimen, which is a standard approach to manage HIV-1 infection and improve the overall health and quality of life of patients.
Check Digit Verification of cas no
The CAS Registry Mumber 149488-17-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,4,8 and 8 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 149488-17:
(8*1)+(7*4)+(6*9)+(5*4)+(4*8)+(3*8)+(2*1)+(1*7)=175
175 % 10 = 5
So 149488-17-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H13BrN4S/c14-10-4-5-12(17-9-10)18-13(19)16-8-6-11-3-1-2-7-15-11/h1-5,7,9H,6,8H2,(H2,16,17,18,19)
