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14949-05-4

N1,N4-bis(chloroacetyl)sulfanilamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 14949-05-4 Structure

  • Basic information

    1. Product Name: N1,N4-bis(chloroacetyl)sulfanilamide
    2. Synonyms: N1,N4-bis(chloroacetyl)sulfanilamide
    3. CAS NO:14949-05-4
    4. Molecular Formula:
    5. Molecular Weight: 325.172
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 14949-05-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N1,N4-bis(chloroacetyl)sulfanilamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N1,N4-bis(chloroacetyl)sulfanilamide(14949-05-4)
    11. EPA Substance Registry System: N1,N4-bis(chloroacetyl)sulfanilamide(14949-05-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 14949-05-4(Hazardous Substances Data)

14949-05-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 14949-05-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,9,4 and 9 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 14949-05:
(7*1)+(6*4)+(5*9)+(4*4)+(3*9)+(2*0)+(1*5)=124
124 % 10 = 4
So 14949-05-4 is a valid CAS Registry Number.

14949-05-4Downstream Products

14949-05-4Relevant articles and documents

Structure-activity relationship of glycine betaine analogs on osmotolerance of enteric bacteria

Abdel-Ghany,Ihnat,Miller,Kunin,Tong

, p. 784 - 789 (1993)

Bacterial cells have the ability to accumulate compatible solutes within the cytoplasm to maintain their osmolarity above that of the extracellular milieu. Glycine betaine (GB) and its biosynthetic precursor choline (Chol) are the major compatible solutes that bacteria accumulate when osmotically challenged. Different osmotically triggered active transport mechanisms have been identified for GB and Chol. In the present study we examined the bioisosteric replacement of the carboxylic group of GB with sulfonic, phosphonic or benzenesulfonamido groups. The sulfonic acid analog (sulfobetaine, compound 3) showed osmoprotectant activity equivalent to that of GB. In addition, we tested the possibility of utilizing GB/Chol transport systems to deliver cytotoxic analogs of GB into three strains of E. coli that differed in their salt resistance. We found that N1-betainyl-N4- (haloacetyl)sulfanilamides (compounds 17c-e) that are GB analogs containing alkylating side chain within their structures inhibited the bacterial growth of the tested standard and salt sensitive strains of E. coli. We also showed that the (N-methyl-cyclic ammonio)methanesulfonates (compounds 21a-c) are able to block Chol transport system in both the standard and the salt- sensitive E. coli strains used. At the concentration used (0.1 mM), none of the tested compounds showed any significant effect on the salt-resistant strain used.

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