14954-35-9

Basic information

• Product Name: 1-phenyl-3-(1,3-thiazol-2-yl)urea
• Synonyms: urea, N-phenyl-N'-2-thiazolyl-
• CAS NO: 14954-35-9
• Molecular Formula: C₁₀H₉N₃OS
• Molecular Weight: 219.263
• Mol File: 14954-35-9.mol
• Article Data: 9

Chemical Properties

• Density: 1.437g/cm³
• Refractive Index: 1.74
• CAS DataBase Reference: 1-phenyl-3-(1,3-thiazol-2-yl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-3-(1,3-thiazol-2-yl)urea(14954-35-9)
• EPA Substance Registry System: 1-phenyl-3-(1,3-thiazol-2-yl)urea(14954-35-9)

Safety Data

• Hazardous Substances Data: 14954-35-9(Hazardous Substances Data)

Usage

Urea Derivative

The compound is derived from urea.

Contains a Phenyl Group

The presence of a phenyl group in the structure.

Contains a Thiazole Ring

The presence of a 1,3-thiazole ring in the structure.

Inhibits Thyroid Peroxidase

PTU can inhibit the enzyme responsible for thyroid hormone production.

Research Tool in Biochemistry and Pharmacology

PTU is used to study various biological processes and drug effects.

Potential Use in Hyperthyroidism Treatment

PTU may be used to treat hyperthyroidism.

Potential Use in Graves' Disease Treatment

PTU may be used to treat Graves' disease.

Potential Anti-Cancer Agent

PTU has shown promise in fighting cancer.

Anti-Inflammatory Properties

PTU has been investigated for its ability to reduce inflammation.

Anti-Fibrotic Properties

PTU has been studied for its potential to prevent tissue scarring and fibrosis.

Versatile Compound

PTU has a wide range of potential applications in medicine and biochemistry.

Upstream product

• 96-50-4 2-thiazolylamine 
• 201230-82-2 carbon monoxide 
• 98-95-3 nitrobenzene 
• 103-71-9 phenyl isocyanate 

Downstream Products

• 97476-89-6 N-dipropylboryl[2-(N-phenyl)carbamoylaminothiazolate] 

Relevant articles and documents

Novel Thiazole Derivatives of Medicinal Potential: Synthesis and Modeling

This paper reports on the synthesis of new thiazole derivatives that could be profitably exploited in medical treatment of tumors. Molecular electronic structures have been modeled within density function theory (DFT) framework. Reactivity indices obtained from the frontier orbital energies as well as electrostatic potential energy maps are discussed and correlated with the molecular structure. X-ray crystallographic data of one of the new compounds is measured and used to support and verify the theoretical results.

GUANIDINE COMPOUNDS AND USE THEREOF

The present invention relates to guanidine compounds and use thereof, and more specifically, to a guanidine derivative having an excellent effect on suppressing cancer-cell proliferation, and suppressing cancer metastasis and recurrence, a method for prep

TYPE III SECRETION INHIBITORS, ANALOGS AND USES THEREOF

The invention, in some aspects, relates to compounds and compositions useful for inhibiting Type III secretion systems in pathogenic bacteria, such as Yersinia Pestis. In some aspects, the invention relates to methods for discovering inhibitors of the Typ