149564-05-6

Basic information

• Product Name: 9-(2',3'-dihydroxypentan-1'-yl)-3-deazaadenine
• Synonyms: 9-(2',3'-dihydroxypentan-1'-yl)-3-deazaadenine;(1R,2S,3R)-3-[4-Amino-1H-imidazo[4,5-c]pyridine-1-yl]-1,2-cyclopentanediol;1-[(1R)-2α,3α-Dihydroxycyclopentan-1β-yl]-1H-imidazo[4,5-c]pyridin-4-amine;3-C-Dihydroxycyclopentyladenine;3-Deaza-DHCaA
• CAS NO: 149564-05-6
• Molecular Formula: C11H14N4O2
• Molecular Weight: 234.25446
• Mol File: 149564-05-6.mol

Chemical Properties

• Boiling Point: 528.7°Cat760mmHg
• Flash Point: 273.5°C
• Appearance: /
• Density: 1.72g/cm³
• PKA: 14.22±0.60(Predicted)
• CAS DataBase Reference: 9-(2',3'-dihydroxypentan-1'-yl)-3-deazaadenine(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(2',3'-dihydroxypentan-1'-yl)-3-deazaadenine(149564-05-6)
• EPA Substance Registry System: 9-(2',3'-dihydroxypentan-1'-yl)-3-deazaadenine(149564-05-6)

Safety Data

• Hazardous Substances Data: 149564-05-6(Hazardous Substances Data)

Upstream product

• 111005-71-1 (-)-9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-3-deazaadenine 

Relevant articles and documents

3-DEAZANEPLANOCIN DERIVATIVES

This invention describes the series of compounds based on the 3-deazaneplanocin A (DZNep) core structure designed to inhibit the function of Polycomb repressive complex 2 (PRC2) proteins.

Use of nucleoside derivatives as cytotoxic agents

Use of a compound of formula (I) wherein R represents, a hydrogen atom; a C1 4 alkyl group;, a group COR1 wherein R1 represents amino or C1 4 alkoxy; or, a group -CH2R2 wherein R2 represents a halogen atom,C1 4 alkylthio, or azido; and, X and Y each independently represent -CH- or -N;, or a physiologically acceptable salt, ester or other physiologically functional derivative thereof,for the manufacture of a medicament for the treatment or prophylaxis of neoplastic growth in an animal.