14959-84-3

Basic information

• Product Name: 3,5-DIIODOBENZOIC ACID
• Synonyms: 4,8-DIHYDROXYQUINOLINE
• CAS NO: 14959-84-3
• Molecular Formula: C₉H₇NO₂
• Molecular Weight: 373.91
• EINECS: -0
• Mol File: 14959-84-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 321 °C(Solv: ethanol (64-17-5))
• Boiling Point: 322.2°C at 760 mmHg
• Flash Point: 148.7°C
• Appearance: /
• Density: 1.337g/cm³
• Vapor Pressure: 0.00015mmHg at 25°C
• Refractive Index: 1.639
• Storage Temp.: 2-8°C
• PKA: 4.48±0.40(Predicted)
• CAS DataBase Reference: 3,5-DIIODOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIIODOBENZOIC ACID(14959-84-3)
• EPA Substance Registry System: 3,5-DIIODOBENZOIC ACID(14959-84-3)

Safety Data

• Hazardous Substances Data: 14959-84-3(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C9H7NO2/c11-7-4-5-10-9-6(7)2-1-3-8(9)12/h1-5,12H,(H,10,11)

Upstream product

• 59-00-7 xanthurenic acid 

Downstream Products

• 1108187-56-9 4-phenylquinolin-8-yl 4-methylbenzenesulfonate 
• 1166262-04-9 4-bromoquinolin-8-yl 4-methylbenzenesulfonate 
• 57334-36-8 4-chloro-8-hydroxyquinoline 
• 1022094-19-4 4-(1H-pyrazol-1-yl)quinolin-8-yl 4-methylbenzenesulfonate 
• 1022094-18-3 (4-chloroquinolin-8-yl)-4-methylbenzenesulfonate 
• 927833-19-0 4-octyloxy-8-tosyloxyquinoline 
• 927833-21-4 4-benzyloxy-8-tosyloxyquinoline 
• 927833-18-9 4-butoxy-8-tosyloxyquinoline 
• 927833-20-3 4-isopropyloxy-8-tosyloxyquinoline 
• 927833-17-8 4-methoxyquinolin-8-yl 4-methylbenzenesulfonate 
• 18996-01-5 toluene-4-sulfonic acid 4-oxo-1,4-dihydro-quinolin-8-yl ester 

Relevant articles and documents

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Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases

There is interest in developing potent, selective, and cell-permeable inhibitors of human ferrous iron and 2-oxoglutarate (2OG) oxygenases for use in functional and target validation studies. The 3-component Betti reaction enables efficient one-step C-7 functionalisation of modified 8-hydroxyquinolines (8HQs) to produce cell-active inhibitors of KDM4 histone demethylases and other 2OG oxygenases; the work exemplifies how a template-based metallo-enzyme inhibitor approach can be used to give biologically active compounds.