149591-20-8

Basic information

• Product Name: 3-(2,4,6-TRIMETHYLPHENYLSULFONYL)-1,2,4-TRIAZOLE
• Synonyms: 3-(2,4,6-TRIMETHYLPHENYLSULFONYL)-1,2,4-TRIAZOLE;3-(2,4,6-Trimethylphenylsulfonyl)-1,2,4-triazole standard
• CAS NO: 149591-20-8
• Molecular Formula: C₁₁H₁₃N₃O₂S
• Molecular Weight: 251.3
• Mol File: 149591-20-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 469.3±55.0 °C(Predicted)
• Appearance: /
• Density: 1.313±0.06 g/cm3(Predicted)
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 6.23±0.20(Predicted)
• CAS DataBase Reference: 3-(2,4,6-TRIMETHYLPHENYLSULFONYL)-1,2,4-TRIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,4,6-TRIMETHYLPHENYLSULFONYL)-1,2,4-TRIAZOLE(149591-20-8)
• EPA Substance Registry System: 3-(2,4,6-TRIMETHYLPHENYLSULFONYL)-1,2,4-TRIAZOLE(149591-20-8)

Safety Data

• Hazardous Substances Data: 149591-20-8(Hazardous Substances Data)

Usage

Uses

3-(2,4,6-Trimethylphenylsulfonyl)-1,2,4-triazole is employed as a herbicide.

Upstream product

• 576-83-0 2,4,6-trimethylphenyl bromide 
• 158091-64-6 3-(2,4,6-trimethylphenyl)thio-1H-1,2,4-triazole 

Relevant articles and documents

Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials

(Graph Presented) Screening of the GSK corporate collection, some 1.9 million compounds, against Plasmodium falciparum (Pf), revealed almost 14000 active hits that are now known as the Tres Cantos Antimalarial Set (TCAMS). Followup work by Calderon et al.

Pharmaceutical use of N-Carbamoylazole derivatives

The present invention relates to use of 1-carbamoylazole derivatives as medicaments and pharmaceutical compositions containing 1-carbamoylazole derivatives as the active ingredient, based on their DPPIV inhibiting effects. The present invention provides a dipeptidyl peptidase IV inhibiting agent comprising a compound represented by the general formula (I):