1496-40-8 Usage
Description
N-(2-AMINO-4-TRIFLUOROMETHYLPHENYL)PIPERIDINE is a chemical compound that features a piperidine ring with an attached amino group and a trifluoromethylphenyl group. N-(2-AMINO-4-TRIFLUOROMETHYLPHENYL)PIPERIDINE is recognized for its potential in pharmacological applications, particularly in the development of new drugs for various medical conditions. The trifluoromethylphenyl group's interaction with biological receptors and enzymes, along with the amino group's capacity for molecular interactions, positions N-(2-AMINO-4-TRIFLUOROMETHYLPHENYL)PIPERIDINE as a promising scaffold in drug design.
Uses
Used in Pharmaceutical Research:
N-(2-AMINO-4-TRIFLUOROMETHYLPHENYL)PIPERIDINE is used as a research compound for its potential in developing new drugs due to its ability to interact with biological receptors and enzymes, which is crucial for the creation of therapeutic agents.
Used in Drug Design:
In the pharmaceutical industry, N-(2-AMINO-4-TRIFLUOROMETHYLPHENYL)PIPERIDINE is used as a molecular scaffold to facilitate the design of drugs, leveraging the trifluoromethylphenyl group's affinity for biological targets and the amino group's capacity for further molecular interactions.
Used in Chemical Research:
N-(2-AMINO-4-TRIFLUOROMETHYLPHENYL)PIPERIDINE is utilized in chemical research laboratories for studying its properties and reactions, contributing to the broader understanding of chemical compounds with similar structures and their potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1496-40-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,9 and 6 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1496-40:
(6*1)+(5*4)+(4*9)+(3*6)+(2*4)+(1*0)=88
88 % 10 = 8
So 1496-40-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H15F3N2/c13-12(14,15)9-4-5-11(10(16)8-9)17-6-2-1-3-7-17/h4-5,8H,1-3,6-7,16H2
1496-40-8Relevant articles and documents
Electroreductive heterocyclization of ortho-piperidino substituted nitro(het)arenes
Begunov, Roman S.,Minyaev, Mikhail E.,Sakulina, Valeria O.,Saverina, Evgeniya A.,Sokolov, Alexandr A.,Syroeshkin, Mikhail A.
, p. 633 - 635 (2020)
Electrochemical reduction of ortho-piperidino substituted nitro(het)arenes in an undivided cell on a lead cathode in 8% HCl gave either 1,2,3,4-tetrahydropyrido[1,2-a]-benzimidazoles or 6,7,8,9-tetrahydropyrido[3′,2′:4,5]- imidazo[1,2-a]pyridines. The red
Copper-catalyzed: Ortho -C(sp2)-H amination of benzamides and picolinamides with alkylamines using oxygen as a green oxidant
Chen, Gong,Huang, Jie,Li, Qiong,Wang, Shui-Bo
, p. 4802 - 4814 (2020/07/13)
A versatile Cu-catalyzed direct ortho-C(sp2)-H amination of benzamides and picolinamides with alkylamines has been achieved. This method employs cheap and eco-friendly copper as a catalyst and oxygen as an oxidant, and also has the advantages of straightf
Trifluoromethyl arylamides with antileukemia effect and intracellular inhibitory activity over serine/arginine-rich protein kinases (SRPKs)
Siqueira, Raoni Pais,Barros, Marcus Vinícius de Andrade,Barbosa, éverton de Almeida Alves,Onofre, Thiago Souza,Gon?alves, Victor Hugo Sousa,Pereira, Higor Sette,Silva Júnior, Abelardo,de Oliveira, Leandro Licursi,Almeida, Márcia Rogéria,Fietto, Juliana Lopes Rangel,Teixeira, Róbson Ricardo,Bressan, Gustavo Costa
, p. 97 - 109 (2017/04/13)
The serine/arginine-rich protein kinases (SRPKs) have frequently been found with altered activity in a number of cancers, suggesting they could serve as potential therapeutic targets in oncology. Here we describe the synthesis of a series of twenty-two tr
