149646-85-5Relevant academic research and scientific papers
Hydridorhodium Diphosphite Catalysts in the Asymmetric Hydroformylation of Styrene
Buisman, Godfried J. H.,Vos, Eric J.,Kamer, Paul C. J.,Leeuwen, Piet W. N. M. van
, p. 409 - 418 (1995)
Chiral diphosphites based on (2R,3R)-butane-2,3-diol, (2R,4R)-pentane-2,4-diol, (2S,5S)-hexane-2,5-diol, (1S,3S)-diphenylpropane-1,3-diol and N-benzyltartarimide as chiral bridges have been used in the rhodium-catalysed asymmetric hydroformylation of styrene.Enantioselectivities up 76percent at 50percent conversion have been obtained with stable hydridorhodium diphosphite catalysts.High regioselectivities (>95percent) and high conversions (>99percent) to 2-phenylpropanal were found under relatively mild reaction conditions .The solution structures of complexes (L = bidentate diphosphite) have been studied; NMR and IR spectroscopic data revealed fluxional behaviour.Depending on the structure of the bridge, the diphosphite adopts equatorial-equatorial or equatorial-axial co-ordination to the rhodium.The structure and stability of the catalysts seems to play a fundamental role in the asymmetric induction.
