1496515-84-4Relevant academic research and scientific papers
Diastereoselective synthesis of stable phosphorus ylides by a three-component reaction between triphenylphosphine, dialkyl acetylenedicarboxylates and 3-(arylsulfonylhydrazono)butanoates
Anary-Abbasinejad, Mohammad,Talebizadeh, Mahdiyeh,Nikmehr, Fereshteh
, p. 385 - 387 (2013/09/12)
Protonation of the reactive 1:1 intermediate produced in the reaction between dialkyl acetylenedicarboxylates and triphenylphosphine by 3-(arylsulfonylhydrazono)butanoates leads to vinylphosphonium salts which undergo Michael addition with the conjugate base of the CH-acid to produce highly functionalised, salt-free phosphorus ylides in a diastereoselective manner and excellent yields.
