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1496524-64-1

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1496524-64-1 Usage

Description

(3-Benzyloxy-4-Methoxyphenyl)(4-Methoxyphenyl)-Methanone is an organic compound that belongs to the class of ketones. It is characterized by its white solid appearance and is primarily used as an intermediate in the synthesis of pharmaceutical compounds, specifically Tolcapone (T535250) and its derivatives.

Uses

Used in Pharmaceutical Industry:
(3-Benzyloxy-4-Methoxyphenyl)(4-Methylphenyl)-Methanone is used as an intermediate in the synthesis of Tolcapone (T535250) and its derivatives for the pharmaceutical industry. Its role in the synthesis process is crucial, as it contributes to the development of medications that can potentially treat various medical conditions.
Chemical Properties:
As a white solid, (3-Benzyloxy-4-Methoxyphenyl)(4-Methoxyphenyl)-Methanone exhibits the typical characteristics of a ketone, including its reactivity and stability in certain chemical reactions. This property makes it a valuable component in the synthesis of complex organic molecules, particularly in the pharmaceutical sector.

Check Digit Verification of cas no

The CAS Registry Mumber 1496524-64-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,9,6,5,2 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1496524-64:
(9*1)+(8*4)+(7*9)+(6*6)+(5*5)+(4*2)+(3*4)+(2*6)+(1*4)=201
201 % 10 = 1
So 1496524-64-1 is a valid CAS Registry Number.

1496524-64-1Relevant articles and documents

Design, synthesis, and fungicidal activity of novel carboxylic acid amides represented by N-benzhydryl valinamode carbamates

Du, Xiu-Jiang,Bian, Qiang,Wang, Hong-Xue,Yu, Shu-Jing,Kou, Jun-Jie,Wang, Zhi-Peng,Li, Zheng-Ming,Zhao, Wei-Guang

, p. 5427 - 5434 (2014/07/21)

Carboxylic acid amide (CAA) fungicides are an important class of agricultural fungicide with oomycete activity and low toxicity toward mammalian cells. To find CAA analogues with high activity against resistant pathogens, a series of substituted N-benzhydryl valinamide carbamate derivatives were designed and synthesized by introducing substituted aromatic rings into valinamide carbamate leads. Bioassays showed that some title compounds exhibited very good in vitro fungicidal activity against Phytophthora capsici and in vivo fungicidal activities against Pseudoperonospora cubensis. Topomer CoMFA was performed to explore the structure-activity relationship on the basis of the in vitro data. The dimethoxy substituted aromatic analogue 9e was found to display higher in vitro fungicidal activity against Phytophthora capsici than iprovalicarb but lower activity than mandipropamid, and higher in vivo fungicidal activity against Pseudoperonospora cubensis than dimethomorph at a dosage of 6.25 μg mL-1. This journal is the Partner Organisations 2014.

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