1496552-28-3

Basic information

• Product Name: D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester
• Synonyms: D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester;SRD;Sofosbuvir impurity C;isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-Dalaninate
• CAS NO: 1496552-28-3
• Molecular Formula: C22H29FN3O9P
• Molecular Weight: 529.4525242
• Mol File: 1496552-28-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.41±0.1 g/cm3(Predicted)
• PKA: 9.39±0.10(Predicted)
• CAS DataBase Reference: D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester(1496552-28-3)
• EPA Substance Registry System: D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester(1496552-28-3)

Safety Data

• Hazardous Substances Data: 1496552-28-3(Hazardous Substances Data)

Usage

Description

D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester is a complex organic compound with a unique chemical structure. It is an epimer and impurity of Sofosbuvir (P839640), which is a pharmaceutical compound used in the treatment of hepatitis C virus (HCV) infections. D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester is characterized by its specific stereochemistry and functional groups, which contribute to its potential applications in the field of pharmaceuticals and drug development.

Uses

Used in Pharmaceutical Industry:
D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester is used as an intermediate in the synthetic preparation of Sofosbuvir analogs for the treatment of hepatitis C virus (HCV) infections. Its unique chemical structure allows for the development of new analogs with potentially improved therapeutic properties and reduced side effects.
Used in Research and Development:
D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester is also used in research and development for the study of its chemical properties, stereochemistry, and potential interactions with biological targets. Understanding the structure-activity relationship of D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester can provide valuable insights into the design and synthesis of new drugs with improved efficacy and safety profiles.
Used in Quality Control and Regulatory Compliance:
As an impurity of Sofosbuvir, D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester is important for quality control and regulatory compliance in the pharmaceutical industry. Its presence in the final drug product must be monitored and controlled to ensure the safety and efficacy of the medication.