149669-45-4 Usage
Description
6-METHYL-3-PIPERIDIN-4-YL-1H-INDOLE, commonly known as MPTP, is a synthetic opioid analog with potent neurotoxic properties. It is known for its ability to induce Parkinson's disease-like symptoms in humans, making it a significant compound in the study and understanding of the condition. MPTP is metabolized in the body to form MPP+, a neurotoxin that selectively destroys dopaminergic neurons in the substantia nigra, leading to characteristic symptoms such as tremors, rigidity, and bradykinesia.
Uses
Used in Pharmaceutical Research:
6-METHYL-3-PIPERIDIN-4-YL-1H-INDOLE is used as a research tool for studying the pathophysiology of Parkinson's disease. Its ability to selectively target and destroy dopaminergic neurons provides valuable insights into the mechanisms underlying the condition and helps in the development of potential therapies.
Used in Drug Development:
6-METHYL-3-PIPERIDIN-4-YL-1H-INDOLE is used as a model compound in the development of drugs aimed at treating Parkinson's disease. By understanding its neurotoxic effects, researchers can design and test potential treatments that may protect or restore the function of dopaminergic neurons, thereby alleviating the symptoms of the disease.
Used in Toxicology Studies:
6-METHYL-3-PIPERIDIN-4-YL-1H-INDOLE is used as a toxicological agent in studies aimed at understanding the mechanisms of neurotoxicity and developing strategies to mitigate the harmful effects of similar compounds. Its role in inducing Parkinson's disease-like symptoms serves as a cautionary example of the potential dangers of synthetic compounds and the importance of thorough safety testing.
Used in Drug Safety and Regulatory Compliance:
6-METHYL-3-PIPERIDIN-4-YL-1H-INDOLE is used as a reference compound in drug safety and regulatory compliance assessments. Its history of accidental synthesis and ingestion highlights the need for stringent safety protocols and regulatory oversight in the development and use of new pharmaceuticals.
Used in Education and Training:
6-METHYL-3-PIPERIDIN-4-YL-1H-INDOLE is used as a case study in educational and training programs related to neurology, pharmacology, and toxicology. Its impact on the understanding of Parkinson's disease and the development of drug safety measures serves as a valuable learning tool for students and professionals in these fields.
Check Digit Verification of cas no
The CAS Registry Mumber 149669-45-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,6,6 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 149669-45:
(8*1)+(7*4)+(6*9)+(5*6)+(4*6)+(3*9)+(2*4)+(1*5)=184
184 % 10 = 4
So 149669-45-4 is a valid CAS Registry Number.
InChI:InChI=1/C14H18N2/c1-10-2-3-12-13(9-16-14(12)8-10)11-4-6-15-7-5-11/h2-3,8-9,11,15-16H,4-7H2,1H3
