149680-18-2 Usage
General Description
(2R)-2-(2,6-difluorophenyl)propionitrile, also known as flufenamic acid, is a chemical compound that belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It is a potent inhibitor of prostaglandin synthesis and is commonly used in the treatment of pain, fever, and inflammation. Flufenamic acid works by blocking the action of the enzyme cyclooxygenase, which is involved in the production of prostaglandins, leading to its anti-inflammatory and analgesic effects. It is also being studied for its potential anticancer properties and as a potential treatment for neurodegenerative diseases. However, it is important to note that the use of flufenamic acid should be closely monitored due to its potential side effects, including gastrointestinal irritation, renal toxicity, and increased risk of cardiovascular events.
Check Digit Verification of cas no
The CAS Registry Mumber 149680-18-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,6,8 and 0 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 149680-18:
(8*1)+(7*4)+(6*9)+(5*6)+(4*8)+(3*0)+(2*1)+(1*8)=162
162 % 10 = 2
So 149680-18-2 is a valid CAS Registry Number.
149680-18-2Relevant articles and documents
Stereoselective synthesis of 2-substituted 6-[1-(2,6-difluorophenyl)ethyl]- 5-methylpyrimidin-4(3H)-ones
Mai,Artico,Rotili,Novakov,Orlinson,Navrotskii,Eremiichuk,Gordeeva
experimental part, p. 1531 - 1534 (2010/03/30)
A procedure has been proposed for the synthesis of 2-(cyclopentylsulfanyl)- 6-[(1R)-1-(2,6-difluorophenyl) ethyl]-5-methylpyrimidin-4(3H)-one through intermediate (3R)-4,4-dimethyl-2-oxotetrahydrofuran-3-yl (2R)-2-(2,6- difluorophenyl)propanoate which was
