149713-24-6

Basic information

• Product Name: (2R,4R)-4-methyl-2-phenyl-tetrahydropyran
• Synonyms: (2R,4R)-4-Methyl-2-phenyltetrahydro-2H-pyran; 2H-pyran, tetrahydro-4-methyl-2-phenyl-, (2R,4R)-
• CAS NO: 149713-24-6
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25
• Mol File: 149713-24-6.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 265.3°C at 760 mmHg
• Flash Point: 110.1°C
• Density: 0.97g/cm³
• Vapor Pressure: 0.0152mmHg at 25°C
• Refractive Index: 1.504
• CAS DataBase Reference: (2R,4R)-4-methyl-2-phenyl-tetrahydropyran(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4R)-4-methyl-2-phenyl-tetrahydropyran(149713-24-6)
• EPA Substance Registry System: (2R,4R)-4-methyl-2-phenyl-tetrahydropyran(149713-24-6)

Safety Data

• Hazardous Substances Data: 149713-24-6(Hazardous Substances Data)

Upstream product

• 39652-50-1 5-hydroxy-3-methyl-5-phenyl-pent-2-enoic acid methyl ester 
• 100-42-5 styrene 
• 172295-01-1 (E)-3-methyl-5-phenyl-4-penten-1-ol 
• 73408-01-2 3-methyl-5-phenyl-4-pentenol 
• 78-79-5 isoprene 
• 100-52-7 benzaldehyde 
• 135569-04-9 <<<(3-methyl-1-phenyl-3-butenyl)oxy>methyl>seleno>benzene 
• 3240-30-0 3-methyl-1-phenyl-pent-4-en-1-one 
• 98-86-2 acetophenone 
• 201145-41-7 (E)-5-hydroxy-3-methyl-5-phenyl-pent-2-enal 
• 19041-17-9 methyl 4-bromo-3-methylbut-2-enoate 
• 1610378-61-4 C₁₉H₂₀O₃ 
• 476687-78-2 (E)-3-methyl-5-phenyl-2-pentene-1,5-diol 

Relevant articles and documents

Catalytic Diastereoselective Hetero-Diels-Alder Reaction of α-Haloacroleins with Alkenes: Construction of 3,4-Dihydropyran

In this Letter, a catalytic diastereoselective hetero-Diels-Alder reaction of α-haloacroleins with less polarized alkenes was developed, and the resulting 3,4-dihydropyrans were produced in high yields with a broad substate scope. Mechanism studies showed that 3,4-dihydropyran was produced from the ring expansion of cyclobutane, which was generated in the ring contraction of the initially formed unstable 3,4-dihydropyran conformer.

gamma-alkenyl ketone and preparation method thereof

The invention discloses a gamma-alkenyl ketone preparation method, wherein the target product can be obtained at high yield and high regioselectivity by using acetophenone and 1,3-butadiene as raw materials in the presence of an organic solvent, a catalyst, an additive and a ligand. According to the invention, the method has advantages of high atom economy, high regioselectivity, high yield and the like, can achieve the efficient conversion from a cheap basic organic chemical product 1,3-butadiene to high-added-value gamma-alkenyl ketone, and uses the cheap catalyst, so that the reaction conditions are neutral and mild, and the experimental operation is safe and simple; and the synthesized gamma-alkenyl ketone is a useful synthetic intermediate, can be subjected to a series of conversionsto obtain a series of drug molecule precursors or key intermediates, and has wide application prospect.

Enantioselective cascade formal reductive insertion of allylic alcohols into the C(O)-C bond of 1,3-diketones: Ready access to synthetically valuable 3-alkylpentanol units

An unprecedented cascade reaction combining dual iron-amine-catalyzed enantioselective functionalization of allylic alcohols and chemoselective acyl transfer is presented. It allows, from diketones and allylic alcohols, preparation of efficiently function