149725-73-5

Upstream product

• 108-24-7 acetic anhydride 
• 108-98-5 thiophenol 
• 5135-37-5 5'-S-phenyl-5'-thioadenosine 
• 121517-91-7 2',3'-Di-O-acetyl-5'-deoxy-5'-adenosine 

Downstream Products

• 149725-79-1 (2R,3R,4S,5S)-2-(6-Amino-purin-9-yl)-5-(fluoro-phenylsulfanyl-methyl)-tetrahydro-furan-3,4-diol 
• 156430-65-8 Acetic acid (2R,3R,4S,5S)-4-acetoxy-5-benzenesulfonylmethyl-2-(6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester 
• 156430-70-5 2',3'-di-O-acetyl-5'-deoxy-5'-(phenylsulfonyl)adenosine 
• 121517-93-9 2',3'-Di-O-acetyl-5'-fluoro-5'-S-phenyl-5'-thioadenosine 
• 121517-91-7 2',3'-Di-O-acetyl-5'-deoxy-5'-adenosine 

Relevant academic research and scientific papers

Nucleic acid related compounds. 80. Synthesis of 5'-S-(alkyl and aryl)-5'-fluoro-5'-thioadenosines with Xenon difluoride or (diethylamido)sulfur trifluoride, hydrolysis in aqueous buffer, and inhibition of S-adenosyl-L-homocysteine hydrolase by derived 'a

Treatment of 5'-S-(alkyl and aryl)-5'-thioadenosine derivatives 2 with XeF2, or the corresponding sulfoxides 3 with DAST/SbCl3, gave diastereomeric 5'-fluoro compounds which were deprotected to give the 5'-S-(alkyl and aryl)-5'-fluor