1497405-14-7Relevant articles and documents
Versatile access to chiral indolines by catalytic asymmetric fischer indolization
Martinez, Alberto,Webber, Matthew J.,Mueller, Steffen,List, Benjamin
, p. 9486 - 9490 (2013/09/23)
"Fisching" for complexity: The chiral Bronsted acid (R)-STRIP catalyzes the asymmetric Fischer indolization of a range of monosubstituted cyclopentanones and cyclohexanones to give chiral fused indolines bearing a quaternary stereogenic center at the 3-position. The method has been extended to include substrates bearing a tethered nucleophile, thus allowing for enantioselective indolization/ring-closing cascades to complex propellanes featuring two vicinal quaternary stereocenters. Copyright