1497405-27-2Relevant academic research and scientific papers
Synthesis and study of halogenated benzylamides of some isocyclic and heterocyclic acids as potential anticonvulsants
Marzanna, Strupińska,Grazyna, Rostafińska-Suchar,Elzbieta, Pirianowicz-Chaber,Mateusz, Grabczuk,Magdalena, Józwenko,Hubert, Kowalczyk,Joanna, Szuba,Monika, Wójcicka,Tracy, Chen,Mazurek, Aleksander P.
, p. 489 - 496 (2015/06/25)
A series of potential anticonvulsants have been synthesized. There are eight fluorobenzylamides and three chlorobenzylamides of isocyclic or heterocyclic acids. Two not halogenated benzylamides were also synthesized to compare the effect of halogenation.
Versatile access to chiral indolines by catalytic asymmetric fischer indolization
Martinez, Alberto,Webber, Matthew J.,Mueller, Steffen,List, Benjamin
supporting information, p. 9486 - 9490 (2013/09/23)
"Fisching" for complexity: The chiral Bronsted acid (R)-STRIP catalyzes the asymmetric Fischer indolization of a range of monosubstituted cyclopentanones and cyclohexanones to give chiral fused indolines bearing a quaternary stereogenic center at the 3-position. The method has been extended to include substrates bearing a tethered nucleophile, thus allowing for enantioselective indolization/ring-closing cascades to complex propellanes featuring two vicinal quaternary stereocenters. Copyright
