149759-26-2 Usage
Uses
Used in Pharmaceutical Industry:
LOE 908 HYDROCHLORIDE is used as a neuroprotective agent for its ability to protect neurons from damage and degeneration. This makes it a valuable compound in the development of treatments for neurological disorders and conditions related to neuronal damage.
Used in Research Applications:
In the field of research, LOE 908 HYDROCHLORIDE is used as a cation channel blocker to study the role of cation channels in various cellular processes. This helps researchers gain a better understanding of the underlying mechanisms and develop targeted therapies for specific conditions.
Used in Drug Development:
LOE 908 HYDROCHLORIDE is utilized as a lead compound in the development of new drugs targeting neurological disorders. Its cation channel blocking and neuroprotective properties make it a promising candidate for further research and potential therapeutic applications.
Biological Activity
Broad spectrum cation channel blocker. Inhibits several cation channels including store-operated calcium channels (SOCs), voltage-operated calcium channels (VOCs), non-selective cation channels (NSCCs), AMPA, NMDA, Na + and K + channels. Neuroprotective; reduces cortical infarct size and improves neurological outcome following middle cerebral artery occlusion.
Check Digit Verification of cas no
The CAS Registry Mumber 149759-26-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,7,5 and 9 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 149759-26:
(8*1)+(7*4)+(6*9)+(5*7)+(4*5)+(3*9)+(2*2)+(1*6)=182
182 % 10 = 2
So 149759-26-2 is a valid CAS Registry Number.
InChI:InChI=1/C41H48N2O9/c1-45-31-16-14-27(37(49-5)39(31)51-7)19-22-43(23-20-28-15-17-32(46-2)40(52-8)38(28)50-6)41(44)35(26-12-10-9-11-13-26)36-30-25-34(48-4)33(47-3)24-29(30)18-21-42-36/h9-17,24-25,35H,18-23H2,1-8H3
