149771-16-4 Usage
Description
2-(Methylthio)-4,5-pyrimidinedicarboxylic Acid, also known as thiamine disulfide, is a chemical compound with the molecular formula C9H8N2O4S2. It is a derivative of pyrimidine and is characterized by its unique structure that includes a methylthio group and two carboxylic acid groups. This versatile compound is often utilized as a pharmaceutical intermediate in the synthesis of drugs and research chemicals, highlighting its importance in the development of new therapeutic agents.
Uses
Used in Pharmaceutical Industry:
2-(Methylthio)-4,5-pyrimidinedicarboxylic Acid is used as a pharmaceutical intermediate for the synthesis of various drugs and research chemicals. Its unique chemical structure allows for the development of new compounds with potential therapeutic benefits.
Used in Neurological Disorder Treatment:
In the field of neurology, 2-(Methylthio)-4,5-pyrimidinedicarboxylic Acid is used as a potential treatment for neurological disorders. Its antioxidant and neuroprotective properties make it a promising candidate for research and development in this area.
Used in Antioxidant Applications:
2-(Methylthio)-4,5-pyrimidinedicarboxylic Acid is used as an antioxidant, which can help protect cells from damage caused by reactive oxygen species. Its ability to neutralize these harmful molecules contributes to its potential use in preventing or treating diseases associated with oxidative stress.
Used in Cancer Treatment Research:
In oncology, 2-(Methylthio)-4,5-pyrimidinedicarboxylic Acid is being studied for its potential role in the treatment of cancer. Its unique chemical properties may offer new avenues for the development of targeted therapies and other cancer treatments.
Used in Other Disease Treatments:
Beyond its applications in neurological disorders, cancer, and antioxidant therapy, 2-(Methylthio)-4,5-pyrimidinedicarboxylic Acid is also being explored for its potential in treating other diseases. Its versatility and unique structure make it a valuable compound for ongoing research and development in the medical field.
Check Digit Verification of cas no
The CAS Registry Mumber 149771-16-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,7,7 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 149771-16:
(8*1)+(7*4)+(6*9)+(5*7)+(4*7)+(3*1)+(2*1)+(1*6)=164
164 % 10 = 4
So 149771-16-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H6N2O4S/c1-14-7-8-2-3(5(10)11)4(9-7)6(12)13/h2H,1H3,(H,10,11)(H,12,13)
149771-16-4Relevant articles and documents
Synthesis and structure-activity relationship studies of conformationally restricted, analogs of 2-chloro-4-trifluoromethylpyrimidine- 5-[N-(3',5'-bis(trifluoromethyl)phenyl)]carboxamide
Palanki, Moorthy S.S.,Erdman, Paul E.,Goldman, Mark E.,Suto, Carla,Suto, Mark J.
, p. 19 - 29 (2007/10/03)
2-Chloro-4-trifluoromethylpyrimidine-5-N[(3,5- bis(trifluoromethyl)phenyl] carboxamide (1) was identified as an inhibitor of AP-1 and NF-κB mediated transcriptional activation. In an effort to identify novel compounds that contain less number of trifluoromethyl groups with comparable potency as 1, several conformationally restricted analogs of I were synthesized in which the pyrimidine ring and the aniline ring were connected through a second 'bridge'. The 7-membered sulfur bridged analog was the most potent in this series, and comparable to 1 in activity.
