149793-79-3Relevant academic research and scientific papers
Carbohydrates to carbocycles: Synthesis of the densely functionalized carbocyclic core of tetrodotoxin by radical cyclization of an anhydro sugar precursor
Alonso, Ricardo A.,Burgey, Christopher S.,Venkateswara Rao,Vite, Gregory D.,Vollerthun, Roland,Zottola, Mark A.,Fraser-Reid, Bert
, p. 6666 - 6672 (1993)
The core of tetrodotoxin is a densely functionalized carbocycle for which an annulated pyranose can be envisaged as a retron. The carbocyclic ring is constructed upon a rigid 1,6-anhydro template which permits the early introduction of the key angular nit
