149805-95-8Relevant academic research and scientific papers
Synthesis of pyridone and pyridine rings by [4+2] hetero-cyclocondensation
Robin, Aélig,Julienne, Karine,Meslin, Jean Claude,Deniaud, David
, p. 9557 - 9559 (2004)
Substituted pyridones and pyridines have been synthesised efficiently by employing iminium salt as a key precursor. These compounds were prepared using tandem [4+2] cycloaddition/deamination between azabutadiene and dienophiles.
Pyrimidinium compound, and preparation method and application thereof
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Paragraph 0317; 0318, (2020/06/05)
The invention relates to a pyrimidinium compound, and a preparation method and an application thereof, and concretely relates to a pyrimidinium compound represented by formula (B2-A) or a stereoisomer, a nitrogen oxide and a salt thereof, an application of the above compounds as insecticides in agriculture, a form of an insecticide composition of the compound, and a method for controlling pests byusing the compounds or the composition. In the formula (B2-A), U, L, R, R, R, R, R, R, R, o and w have the meanings described in the invention.
Furanone derivatives, preparation method and use thereof
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Paragraph 0191; 0192; 0195; 0196, (2019/05/04)
The invention relates to a novel selective cyclooxygenase-2 inhibitor compound, a preparation method and use and belongs to the field of chemical drugs. The compound represented by a formula (I) shown in the description can be used for inhibiting cyclooxy
INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF
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Paragraph 0291, (2017/09/05)
The present invention relates to novel compounds which are capable of inhibiting certain amine oxidase enzymes. These compounds are useful for treatment of a variety of indications, e.g., fibrosis, cancer and/or angiogenesis in human subjects as well as i
NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING INHIBITORY EFFECT ON PRODUCTION OF KYNURENINE
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Paragraph 0213, (2013/03/28)
The present invention provides a nitrogen-containing heterocyclic compound or a pharmaceutically acceptable salt thereof having an inhibitory effect on the production of kynurenine, represented by formula (I): (wherein R6 and R7 may be the same or different and each represent a hydrogen atom or the like, R8, R9, R19, and R11 may be the same or different and each represent a hydrogen atom or the like, R1 represents lower alkyl which may be substituted with cycloalkyl, or the like, and R3 represents optionally substituted aryl or an optionally substituted heterocyclic group).
Substituted dipyridylethenes and -ethynes and key pyridine building blocks
Windscheif,Vogtle
, p. 87 - 92 (2007/10/02)
Various new 2,5-disubstituted pyridines were prepared. The 2-substituted 5-formylpyridines 8, 15a-b were obtained by reduction of the nicotinic acid 3, hydrolysis of the bis(morpholino)methylpyridine 6 or the reaction of 5-bromopyridines 12 and 14 with lithium butoxide in DMF. Dipyridylethenes 16a-b,e were synthesized by Wadsworth-Emmons reaction with pyridyl phosphonate 7 or by coupling of the aldehydes by McMurry reaction to the ethenes 16c-d. After bromination of the C = C double bond of the dipyridylethenes 16a-d, dipyridylacetylenes 18a-d were obtained via elimination of the 1,2-dipyridyl-1,2-dibromoethanes 17a-d.
