149845-06-7 Usage
Chemical Properties
White Crystalline Solid
Uses
Different sources of media describe the Uses of 149845-06-7 differently. You can refer to the following data:
1. A selective HIV protease inhibitor. Antiviral.
2. Antiviral;Protease inhibitor
3. Saquinavir mesylate may be used in cell signaling and immunology studies.
Brand name
Invirase (Roche).
General Description
Saquinavir is a peptidomimetic hydroxyethylamine inhibitor, which is used to treat human immunodeficiency virus (HIV) infection.
Hazard
Moderately toxic by ingestion.
Biochem/physiol Actions
Saquinavir is an HIV Protease Inhibitor used in antiretroviral therapy. It inhibits both HIV-1 and HIV-2 proteases. Studies have also looked at saquinavir as a possible anti-cancer agent.
Check Digit Verification of cas no
The CAS Registry Mumber 149845-06-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,8,4 and 5 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 149845-06:
(8*1)+(7*4)+(6*9)+(5*8)+(4*4)+(3*5)+(2*0)+(1*6)=167
167 % 10 = 7
So 149845-06-7 is a valid CAS Registry Number.
InChI:InChI=1/C38H50N6O5.CH4O3S/c1-38(2,3)43-37(49)32-20-26-14-7-8-15-27(26)22-44(32)23-33(45)30(19-24-11-5-4-6-12-24)41-36(48)31(21-34(39)46)42-35(47)29-18-17-25-13-9-10-16-28(25)40-29;1-5(2,3)4/h4-6,9-13,16-18,26-27,30-33,45H,7-8,14-15,19-23H2,1-3H3,(H2,39,46)(H,41,48)(H,42,47)(H,43,49);1H3,(H,2,3,4)/t26-,27+,30-,31-,32-,33+;/m0./s1
149845-06-7Relevant articles and documents
NOVEL POLYMORPHS OF SAQUINAVIR
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Page/Page column 3, (2012/02/15)
The present invention provides novel polymorphs of saquinavir, processes for their preparation and pharmaceutical compositions comprising them. The present invention also provides a process for purification of saquinavir. The present invention further provides a novel process for preparation of known saquinavir crystalline form I.