2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE, also known as 2-MPMDQ, is a novel class of compounds that belong to the α1-adrenoceptor antagonists. It is characterized by its unique chemical structure, which contributes to its pharmacological properties and potential applications in the medical field.
149847-77-8
Post Buying Request-
-
Basic information
- Product Name: 2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE
- Synonyms: 2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE;2-MPMDQ
- CAS NO:149847-77-8
- Molecular Formula: C23H27N5O2
- Molecular Weight: 405.49
- EINECS: N/A
- Product Categories: N/A
- Mol File: 149847-77-8.mol
-
Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: Store at RT
- Solubility: <20.27mg/ml in DMSO
- CAS DataBase Reference: 2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE(CAS DataBase Reference)
- NIST Chemistry Reference: 2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE(149847-77-8)
- EPA Substance Registry System: 2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE(149847-77-8)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 149847-77-8(Hazardous Substances Data)
149847-77-8 Suppliers
Recommended suppliers
149847-77-8 Usage
Uses
Used in Pharmaceutical Industry:2-MPMDQ is used as an anti-hypertensive agent for the treatment of hypertension. It functions by blocking the α1-adrenoceptors, which play a crucial role in regulating blood pressure. By antagonizing these receptors, 2-MPMDQ helps to lower blood pressure and provide relief from hypertension-related symptoms.
Biological Activity
Potent and selective α 1 -adrenoceptor antagonist; hypotensive.references
[1]. chern jw, tao pl, yen mh, et al. studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives: a novel class of potent and selective alpha 1-adrenoceptor antagonists and antihypertensive agents. j med chem, 1993, 36(15): 2196-2207.Check Digit Verification of cas no
The CAS Registry Mumber 149847-77-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,8,4 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.Calculate Digit Verification of CAS Registry Number 149847-77:
(8*1)+(7*4)+(6*9)+(5*8)+(4*4)+(3*7)+(2*7)+(1*7)=188
188 % 10 = 8
So 149847-77-8 is a valid CAS Registry Number.
149847-77-8Upstream product
149847-77-8Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 149847-77-8
2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE
