149859-17-6

Basic information

• Product Name: N-[(2S)-3-methyl-2-{[4-(morpholin-4-ylcarbonyl)benzoyl]amino}butanoyl]-1-(5,5,6,6,6-pentafluoro-2-methyl-4-oxohexan-3-yl)-L-prolinamide
• CAS NO: 149859-17-6
• Molecular Formula: C₂₉H₃₇F₅N₄O₆
• Molecular Weight: 632.6193
• Mol File: 149859-17-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 721.6°C at 760 mmHg
• Flash Point: 390.2°C
• Density: 1.297g/cm³
• Vapor Pressure: 1.12E-20mmHg at 25°C
• Refractive Index: 1.513
• CAS DataBase Reference: N-[(2S)-3-methyl-2-{[4-(morpholin-4-ylcarbonyl)benzoyl]amino}butanoyl]-1-(5,5,6,6,6-pentafluoro-2-methyl-4-oxohexan-3-yl)-L-prolinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(2S)-3-methyl-2-{[4-(morpholin-4-ylcarbonyl)benzoyl]amino}butanoyl]-1-(5,5,6,6,6-pentafluoro-2-methyl-4-oxohexan-3-yl)-L-prolinamide(149859-17-6)
• EPA Substance Registry System: N-[(2S)-3-methyl-2-{[4-(morpholin-4-ylcarbonyl)benzoyl]amino}butanoyl]-1-(5,5,6,6,6-pentafluoro-2-methyl-4-oxohexan-3-yl)-L-prolinamide(149859-17-6)

Safety Data

• Hazardous Substances Data: 149859-17-6(Hazardous Substances Data)

Upstream product

• 175012-22-3 4-(Morpholine-4-carbonyl)-benzoyl chloride 

Relevant articles and documents

Inhibition of human neutrophil elastase with peptidyl electrophilic ketones. 2. Orally active p(G)-Val-Pro-Val pentafluoroethyl ketones

Valylprolylvalyl pentafluoroethyl ketones with different N-protecting groups were evaluated in vitro and in vivo as inhibitors of human neutrophil elastase (HNE). Several of these compounds were found to be orally active in HNE-induced rat and hamster lun