149890-37-9Relevant academic research and scientific papers
ISOMERIZATION UNDER THE INFLUENCE OF p-TOLUENESULFONIC ACID.
Kovshev,Karamysheva,Torgova,Geivandova,Roitman
, p. 1069 - 1070 (2007/10/02)
The authors have investigated the influence of a mild acid isomerization catalyst, p-toluenesulfonic acid (TSA), on 4-butyl- (Ia) and 4-hexyl- (Ib) cyclohexanecarboxylic acids and their methyl esters (IIa, IIb). It is found that p-toluenesulfonic acid is an effective catalyst of cis-trans isomerization of 4-alkylcyclohexanecarboxylic acids and their esters; removal of water from the reaction medium raises the isomerization rate. Esters of alkylcyclohexanecarboxylic acids are isomerized at higher rates than the acids themselves. A probable mechanism of the acid-catalyzed isomerization reaction is proposed.
