149902-20-5Relevant academic research and scientific papers
Asymmetric synthesis of four isomers of 2-C-trifluoromethylerythritol
Wang, Hua,Zhao, Xiaoming,Li, Youhua,Lu, Long
, p. 3278 - 3281 (2006)
Optically active 2-C-trifluoromethylerythritols, analogues of 2-C-methylerythritol, which is a key intermediate in the biosynthesis of isoprenoid with a mevalonate-independent route, were conveniently synthesized from 1,1,1-trifluoro-2,3-epoxypropane.
Study of IspH, a key enzyme in the methylerythritol phosphate pathway using fluoro-substituted substrate analogues
Xiao, Youli,Chang, Wei-Chen,Liu, Hung-Wen,Liu, Pinghua
supporting information; experimental part, p. 5912 - 5915 (2011/12/16)
IspH, a [4Fe-4S]-cluster-containing enzyme, catalyzes the reductive dehydroxylation of 4-hydroxy-3-methyl-butenyl diphosphate (HMBPP) to isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) in the methylerythritol phosphate pathway. Studies
Improved microwave-assisted ring opening of 1,1,1-trifluoro-2,3- epoxypropane: Synthesis of new 3-alkoxy-1,1,1-trifluoropropan-2-ols
Rayo, Josep,Munoz, Lourdes,Rosell, Gloria,Bosch, Ma. Pilar,Guerrero, Angel
experimental part, p. 3117 - 3120 (2010/11/02)
A highly efficient and environmentally friendly method for the synthesis of 3-alkoxy-1,1,1-trifluoropropan-2-ols is presented. The approach involves ring-opening reaction of 1,1,1-trifluoro-2,3-epoxypropane with structurally different long-chain alcohols
Synthesis of a fluorinated ganciclovir analog
Sznaidman, Marcos L.,Beauchamp, Lilia M.
, p. 1315 - 1321 (2007/10/03)
The synthesis of a new ganciclovir analog with a trifluoromethyl group in the acyclic chain is described.
