149912-72-1Relevant articles and documents
Synthesis of 3-Mercapto-2(5H)-furanones via Reaction of Dilithio-2,4-thiazolidinedione with α-Halo Ketones.
Zask, Arie,Nowicki, James W.,Jirkovsky, Ivo,Engen, Donna Van
, p. 2719 - 2722 (2007/10/02)
A novel synthesis of 3-mercapto-2(5H)-furanones is reported based upon the reaction of dilithio-2,4-thiazolidinedione with α-halo ketones.Substitution at the furanone 4- and 5-positions may be controlled by the choice of α-halo ketone.
5-(2-hydroxy-1-arylethylidene)- and 5-(2-oxo-1-arylethylidene)-2,4-thiazolidinediones and derivatives thereof
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, (2008/06/13)
5-(2-Hydroxy-1-phenyl (or-1-naphthalenyl)ethylidene) and 5-(2-oxo-1-phenyl (or 1-naphthalenyl)ethylidene)-2,4-thiazolidinediones and derivatives thereof are useful in lowering blood glucose levels in a hyperglycemic laboratory animal model and are thus useful in the treatment of diabetes mellitus.