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(4S,4aS,5aR,12aS)-9-Amino-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide sulfate is a complex organic compound with a naphthacenecarboxamide core and a sulfate group. It is a derivative of the antibiotic doxorubicin and possesses a molecular formula of C46H65N13O13S, along with a molecular weight of 1030.15 g/mol. (4S,4aS,5aR,12aS)-9-Amino-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide sulfate is characterized by its unique stereochemistry and functional groups, which contribute to its potent chemotherapeutic properties.

149934-20-3

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149934-20-3 Usage

Uses

Used in Oncology:
(4S,4aS,5aR,12aS)-9-Amino-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide sulfate is used as a chemotherapeutic agent for the treatment of cancer. Its specific antitumor activity and potent efficacy make it a valuable drug in oncology. It is particularly effective against various types of cancer, including solid tumors, due to its ability to target and kill cancer cells while minimizing damage to healthy cells.
Used in Drug Development:
As a derivative of doxorubicin, (4S,4aS,5aR,12aS)-9-Amino-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide sulfate holds potential for further drug development and optimization. Researchers can explore its structure-activity relationships and modify its chemical properties to develop new and improved anticancer drugs with enhanced selectivity, reduced side effects, and increased potency.
Used in Medicinal Chemistry Research:
The unique structure and properties of (4S,4aS,5aR,12aS)-9-Amino-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide sulfate make it an interesting subject for medicinal chemistry research. Scientists can study its interactions with biological targets, such as DNA, proteins, and enzymes, to gain insights into its mechanism of action and identify potential opportunities for drug design and optimization.

Check Digit Verification of cas no

The CAS Registry Mumber 149934-20-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,9,3 and 4 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 149934-20:
(8*1)+(7*4)+(6*9)+(5*9)+(4*3)+(3*4)+(2*2)+(1*0)=163
163 % 10 = 3
So 149934-20-3 is a valid CAS Registry Number.

149934-20-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide,sulfuric acid

1.2 Other means of identification

Product number -
Other names (4S,4aS,5aR,12aS)-9-Amino-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamidesulfate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:149934-20-3 SDS

149934-20-3Upstream product

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