149965-41-3

Basic information

• Product Name: 4-bromo-2-(bromomethyl)-1-chlorobenzene
• Synonyms: 4-bromo-2-(bromomethyl)-1-chlorobenzene;5-Bromo-2-chlorobenzyl bromide
• CAS NO: 149965-41-3
• Molecular Formula: C₇H₅Br₂Cl
• Molecular Weight: 284.3756
• Mol File: 149965-41-3.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 286.531 °C at 760 mmHg
• Flash Point: 140.402 °C
• Appearance: /
• Density: 1.933
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-bromo-2-(bromomethyl)-1-chlorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-(bromomethyl)-1-chlorobenzene(149965-41-3)
• EPA Substance Registry System: 4-bromo-2-(bromomethyl)-1-chlorobenzene(149965-41-3)

Safety Data

• Hazardous Substances Data: 149965-41-3(Hazardous Substances Data)

Usage

General Description

4-bromo-2-(bromomethyl)-1-chlorobenzene is a chemical compound with the molecular formula C7H4Br2Cl. It consists of a benzene ring with a chlorine atom and two bromine atoms attached at different positions. The compound is commonly used in organic synthesis and chemical reactions, and it is also employed as an intermediate in the manufacturing of pharmaceuticals and agricultural chemicals. Its unique structure and reactivity make it useful in a variety of applications, including as a building block in the synthesis of more complex organic compounds. The chemical properties and structure of 4-bromo-2-(bromomethyl)-1-chlorobenzene make it an important component in the field of organic chemistry.

Upstream product

• 54932-72-8 2-chloro-5-bromotoluene 
• 95-53-4 o-toluidine 
• 583-75-5 4-Bromo-2-methylaniline 
• 7789-60-8 phosphorus tribromide 
• 149965-40-2 5-bromo-2-chlorobenzyl alcohol 
• 21739-92-4 5-bromo-2-chlorobenzoic acid 

Downstream Products

• 879403-77-7 4-bromo-1-chloro-2-(phenoxymethyl)benzene 
• 461432-23-5 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene 
• 258885-61-9 4-(2-chloro-5-phenylbenzyl)-5-methoxy-2-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 258885-59-5 4-(5-bromo-2-chlorobenzyl)-5-methoxy-2-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 915095-89-5 (S)-4-bromo-1-chloro-2-(4-tetrahydrofuran-3-yloxy-benzyl)benzene 
• 1057216-52-0 C₈H₅BrClN 
• 203314-33-4 C₉H₈BrClO₂ 
• 177985-34-1 5-bromo-2-chlorophenylacetic acid 
• 945999-91-7 N-(5-bromo-2-chlorobenzyl)cyclopropanamine 

Relevant articles and documents

Preparation method of SGLT2 inhibitor-empagliflozin

The invention relates to a preparation method of a SGLT2 inhibitor-empagliflozin. The preparation method includes: using 2-methylaniline as a starting raw material, subjecting the starting raw material to bromination, diazotization, chlorination and bromination, and enabling the starting raw material to be in friedel-crafts alkylation reaction with (S)-3-phenoxy tetrahydrofuran to obtain an intermediate-(S)-3-(4-(5-bromo-2-chlorobenzyl)phenoxy) tetrahydrofuran; subjecting the intermediate and 2, 3, 4, 6-tetra-O-trimethylsilyl-D-glucolactone to condensation, etherification and methoxy removal.The preparation method has the advantages that compared with existing synthetic methods, 2-methylaniline is used as the starting raw material, so that the raw material is low in cost and easy to get,the process is easy for industrialization, and a synthetic route is short and easy to operate; in the process of preparation, temperature conditions are easy to control, reaction conversion rate is high, and total yield is up to higher than 75%. In addition, through the preparation method, the inhibitor is less prone to isomerization, impurities are few, and purity of the inhibitor can be improvedto higher than 99%.

5-bromo-2-chloro -4 the-oxethyl diphenylmothane [...] preparation method

The invention relates to the chemical field and particularly relates to a novel synthesis method for preparing a key intermediate 5-bromine-2-chlorine-4'-ethyoxyl diphenylmethane of a drug dapagliflozin for treating diabetes mellitus II. The preparation method comprises the following steps: enabling a starting raw material ortho-toluidine to firstly perform bromization and then perform chlorination after diazotization on a benzene ring with N-bromo-succinimide; then, in the presence of a halogenating agent, performing halogenating reaction of beta-position; and finally, performing Friedel-Crafts alkylation synthesis with phenetole, thereby obtaining the key intermediate. The preparation method is simple and convenient, economical and relatively high in reaction yield in each step, and suitable for industrial production.

STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI

The present invention relates to novel strobilurine type compounds, to compositions comprising at least one such compound, to methods for combating phytopathogenic fungi, to the use of such compounds and to seeds coated with at least one such compound. (I