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The chemical "5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-[[4-(tert-butyl)phenoxy]acetyl]guanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite" is a complex organic compound used in the synthesis of oligonucleotides, specifically DNA and RNA. It is a protected guanosine phosphoramidite, which is a building block for the construction of nucleic acids. The compound features a guanosine base with a 5'-O-(4,4-dimethoxytrityl) group for protection, a 2'-O-[(tert-butyl)dimethylsilyl] group for additional stability, and a N-[[4-(tert-butyl)phenoxy]acetyl] group for further protection of the guanosine base. The 3'-end is modified with a 2-cyanoethyl-N,N-diisopropyl phosphoramidite group, which is essential for the coupling reaction in the oligonucleotide synthesis process. This specific compound is designed to facilitate the controlled and efficient assembly of nucleic acid sequences in a laboratory setting, with the protective groups being removed at appropriate stages to yield the desired oligonucleotide product.

149989-68-4

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Basic information
1. Product Name: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-[[4-(tert-butyl)phenoxy]acetyl]guanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
2. Synonyms: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-[[4-(tert-butyl)phenoxy]acetyl]guanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;5'-O-DMT-2'-TBDMS-rG(N-tac)-3'-CEDPA;2'-O-[(tert-butyl)dimethylsilyl]-N-[[4-(tert-butyl)phenoxy]acetyl]guanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;4-tert-butylbenzyl 9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(tert-butyldimethylsilyloxy)-4-((2-cyanoethoxy)(diisopropylamino)phosphinooxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-ylcarbamate;DMT-2′O-TBDMS-rG(tac) Phosphoramidite;DMT-2'O-TBDMS-RG(TAC) AMIDITE 10G, SINGL;DMT-2'O-TBDMS-rG(tac) Amidite 0.5g, AB,;DMT-2'O-TBDMS-rG(tac) Amidite 2,5g, 12Pa
3. CAS NO:149989-68-4
4. Molecular Formula: C58H76N7O10PSi
5. Molecular Weight: 1090.34
6. EINECS: N/A
7. Product Categories: N/A
8. Mol File: 149989-68-4.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: ?20°C
8. Solubility: N/A
9. PKA: 8.71±0.20(Predicted)
10. CAS DataBase Reference: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-[[4-(tert-butyl)phenoxy]acetyl]guanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite(CAS DataBase Reference)
11. NIST Chemistry Reference: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-[[4-(tert-butyl)phenoxy]acetyl]guanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite(149989-68-4)
12. EPA Substance Registry System: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-[[4-(tert-butyl)phenoxy]acetyl]guanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite(149989-68-4)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany: 3
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 149989-68-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 149989-68-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,9,8 and 9 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 149989-68:
(8*1)+(7*4)+(6*9)+(5*9)+(4*8)+(3*9)+(2*6)+(1*8)=214
214 % 10 = 4
So 149989-68-4 is a valid CAS Registry Number.

149989-68-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	DMT-2′O-TBDMS-rG(tac) Phosphoramidite

1.2 Other means of identification

Product number	-
Other names	5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-[[4-(tert-butyl)phenoxy]acetyl]guanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:149989-68-4 SDS

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