15000-91-6 Usage
General Description
1-(1-bromonaphthalen-2-yl)-N,N-dimethylmethanamine is a chemical compound that is derived from naphthalene, a highly flammable and aromatic hydrocarbon. 1-(1-bromonaphthalen-2-yl)-N,N-dimethylmethanamine contains a bromine atom and a dimethylamine group, making it a potentially hazardous substance if not properly handled. It is commonly used in organic synthesis and as a reagent in chemical reactions. The bromine atom in the compound makes it reactive and capable of participating in various substitution and elimination reactions. In addition, the dimethylamine group confers basic properties to the compound, making it useful in the synthesis of pharmaceuticals and other organic products. However, due to its potential hazards and reactivity, proper safety precautions must be taken when working with 1-(1-bromonaphthalen-2-yl)-N,N-dimethylmethanamine.
Check Digit Verification of cas no
The CAS Registry Mumber 15000-91-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,0,0 and 0 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 15000-91:
(7*1)+(6*5)+(5*0)+(4*0)+(3*0)+(2*9)+(1*1)=56
56 % 10 = 6
So 15000-91-6 is a valid CAS Registry Number.
15000-91-6Relevant articles and documents
Enantiospecific Synthesis of ortho-Substituted 1,1-Diarylalkanes by a 1,2-Metalate Rearrangement/anti-SN2′ Elimination/Rearomatizing Allylic Suzuki–Miyaura Reaction Sequence
Rubial, Belén,Collins, Beatrice S. L.,Bigler, Raphael,Aichhorn, Stefan,Noble, Adam,Aggarwal, Varinder K.
, p. 1366 - 1370 (2019/01/04)
The one-pot sequential coupling of benzylamines, boronic esters, and aryl iodides has been investigated. In the presence of an N-activator, the boronate complex formed from an ortho-lithiated benzylamine and a boronic ester undergoes stereospecific 1,2-metalate rearrangement/anti-SN2′ elimination to form a dearomatized tertiary boronic ester. Treatment with an aryl iodide under palladium catalysis leads to rearomatizing γ-selective allylic Suzuki–Miyaura cross-coupling to generate 1,1-diarylalkanes. When enantioenriched α-substituted benzylamines are employed, the corresponding 1,1-diarylalkanes are formed with high stereospecificity.
