150004-34-5Relevant academic research and scientific papers
Dipeptide mimetics can substitute for the receptor activation domain resulting in highly potent analogues of hPTH(1-36) fragment
Waelchli, Rudolf,Gamse, Rainer,Bauer, Wilfried,Meigel, Harald,Lier, Edouard,Feyen, Jean H.M.
, p. 1151 - 1156 (2007/10/03)
A series of hPTH(1-36) analogues were prepared to study the role of the first peptide bond between residues Ser1-Val2. Some of these analogues were found to show high affinity binding in intact opossum kidney (OK-1) cells and were very active in their ability to stimulate adenylate cyclase production in intact OK-1 cells, rat UMR106-06 osteosarcoma cells, and SaOS-2 human osteosarcoma cells.
