150008-25-6 Usage
General Description
The chemical 1-Pyrrolidinecarboxylicacid,3-(hydroxyimino)-,1,1-dimethylethylester(9CI) is a compound that is commonly known as a proline derivative. It is a carboxylic acid ester with a hydroxyimino group and a tert-butyl group attached to the pyrrolidine ring. This chemical is used in various research and pharmaceutical applications as a building block for the synthesis of proline-containing peptides and peptidomimetics. Additionally, it has potential applications in the development of new drugs and therapeutic agents due to its ability to modulate biological processes related to proline metabolism. However, proper handling and safety precautions should be followed when working with this compound due to its potential hazards and toxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 150008-25-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,0,0 and 8 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 150008-25:
(8*1)+(7*5)+(6*0)+(5*0)+(4*0)+(3*8)+(2*2)+(1*5)=76
76 % 10 = 6
So 150008-25-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H16N2O3/c1-9(2,3)14-8(12)11-5-4-7(6-11)10-13/h13H,4-6H2,1-3H3/b10-7-
150008-25-6Relevant articles and documents
Synthesis and biological activity of novel 1β-Methylcarbapenems with oxyiminopyrrolidinylamide moiety
Lee, Ji Hoon,Lee, Kyung Seok,Kang, Yong Koo,Yoo, Kyung Ho,Shin, Kye Jung,Kim, Dong Chan,Kong, Jae Yang,Lee, Yeonhee,Lee, Sook Ja,Kim, Dong Jin
, p. 4399 - 4403 (2007/10/03)
The synthesis and antibacterial activity of novel 1β- methylcarbapenems 1a-f bearing oxyiminopyrrolidinylamide moiety at C-5 position of pyrrolidine are described. Most compounds exhibited comparable antibacterial activity to meropenem against a wide range of Gram-positive and Gram-negative organisms including Pseudomonas aeruginosa isolates. Of these carbapenems, 1a showed potent and broad spectrum of antibacterial activity and similar stability to DHP-I to meropenem. Against clinical isolates of 40 Gram-negative bacterial species including MDR and ESBL-producing strains, the selected carbapenem 1a possessed excellent in vitro activity except for MDR P. aeruginosa, and was comparable in potency to meropenem.
