150020-64-7

Basic information

• Product Name: 6-CHLOROIMIDAZO[2,1-B][1,3]THIAZOLE-5-SULFONYL CHLORIDE
• Synonyms: 6-CHLOROIMIDAZO[2,1-B]THIAZOLE-5-SULFONYL CHLORIDE;6-CHLOROIMIDAZO[2,1-B][1,3]THIAZOLE-5-SULFONYL CHLORIDE;BUTTPARK 37\12-52;6-Chloroimidazo[2,1-b][1,3]thiazole-5-sulphonyl chloride;6-Chloroimidazo[2,1-b]thiazole-5-sulfonyl
• CAS NO: 150020-64-7
• Molecular Formula: C₅H₂Cl₂N₂O₂S₂
• Molecular Weight: 257.12
• Product Categories: Heterocycles
• Mol File: 150020-64-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: 137 °C
• Appearance: /
• Density: 2.05 g/cm³
• Refractive Index: 1.817
• PKA: -5.33±0.40(Predicted)
• Water Solubility: Sparingly soluble in water.(0.26 g/L) (25°C),
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 6-CHLOROIMIDAZO[2,1-B][1,3]THIAZOLE-5-SULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLOROIMIDAZO[2,1-B][1,3]THIAZOLE-5-SULFONYL CHLORIDE(150020-64-7)
• EPA Substance Registry System: 6-CHLOROIMIDAZO[2,1-B][1,3]THIAZOLE-5-SULFONYL CHLORIDE(150020-64-7)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39
• RIDADR: 3261
• HazardClass: 8
• Hazardous Substances Data: 150020-64-7(Hazardous Substances Data)

Usage

Uses

It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor.

InChI:InChI=1/C5H2Cl2N2O2S2/c6-3-4(13(7,10)11)9-1-2-12-5(9)8-3/h1-2H

Upstream product

• 23576-81-0 6-chloroimidazo[2,1-b]thiazole 

Downstream Products

• 112582-89-5 6-chloro-imidazo[2,1-b]thiazole-5-sulfonic acid amide 
• 1190482-07-5 6-chloro-N-(1-oxo-2,3-dihydro-1H-inden-4-yl)imidazo[2,1-b][1,3]thiazole-5-sulfonamide 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF 6-SUBSTITUTED-IMIDAZO [2,1-B] THIAZOLE-5-SULFONYL HALIDE

The present invention is related to the a new process for the preparation of 6-substituted-imidazo [2,1 -b] thiazole-5-sulfonyl halides of formula (I), comprising gradually adding a compound of formula (Il), into a heated solution of R1SO3H where R1 represents F or Cl, and R2 represents H, F, Cl, Br, S, (C1C6)alkyl, (C1-C6)alkoκy or triftuoromethyl.