150056-86-3Relevant academic research and scientific papers
Synthesis of 6-substituted-4-hydroxy-2-pyridinones via intramolecular ketene trapping of functionalized enamine-dioxinones
Patel, Bhavesh H.,Mason, Andrew M.,Barrett, Anthony G.M.
supporting information; experimental part, p. 5156 - 5159 (2011/11/29)
The synthesis of various 6-substituted-4-hydroxy-2-pyridinones is reported. The functionalized keto-dioxinones were constructed via a diethylzinc mediated crossed Claisen condensation reaction and subsequent enamine formation, thermolysis, and cyclization
Retro-Ene Reactions in Heterocyclic Synthesis. II. A Facile Synthetic Method for 4-Hydroxy-2-pyridones
Ito, Kunio,Miyajima, Shingo
, p. 1037 - 1044 (2007/10/02)
Schiff's bases 1 derived from ketones and t-butylamine reacted with diphenyl malonate, diphenyl methylmalonate and diphenyl phenylmalonate to give 4-hydroxy-2-pyridones 4-6.Schiff's bases 1 on reaction with trimethyl methanetricarboxylate afforded 4-hydro
