150094-28-3Relevant academic research and scientific papers
Azulene derivatives as TXA2/PGH2 receptor antagonists - II. Synthesis and biological activity of 6-mono- and 6-dihydroxylated-isopropylazulenes
Yokota, Masayuki,Uchibori, Satoko,Hayashi, Hiromi,Koyama, Rei,Kosakai, Kazuhiro,Wakabayashi, Shuichi,Tomiyama, Tsuyoshi
, p. 575 - 591 (2007/10/03)
In order to examine the correlation between activity and hydrophilicity of the side chain of sodium 3-[4-(4-chlorobenzenesulfonylamino)butyl]-6- isopropylazulene-1-sulfonate (KT2-962), a non-prostanoid TXA2/PGH2 receptor antagonist,
Simple and selective oxidation of 6-alkylazulene derivatives
Yokota,Koyama,Hayashi,Uchibori,Tomiyama,Miyazaki
, p. 1418 - 1428 (2007/10/02)
The simple and regioseletive oxidation of 6-alkylazulene derivatives with an electron-withdrawing substituent at the 1-position of the azulene ring is described. Oxidation with molecular oxygen proceeds smoothly in the presence of a base such as potassium
