1501-32-2

Basic information

• Product Name: 3,3a-dihydropyrrolo[1,2-a]quinoxaline-1,4(2H,5H)-dione
• CAS NO: 1501-32-2
• Molecular Formula: C₁₁H₁₀N₂O₂
• Molecular Weight: 202.2093
• Mol File: 1501-32-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 474.6°C at 760 mmHg
• Flash Point: 240.8°C
• Density: 1.41g/cm³
• Vapor Pressure: 3.56E-09mmHg at 25°C
• Refractive Index: 1.669
• CAS DataBase Reference: 3,3a-dihydropyrrolo[1,2-a]quinoxaline-1,4(2H,5H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3a-dihydropyrrolo[1,2-a]quinoxaline-1,4(2H,5H)-dione(1501-32-2)
• EPA Substance Registry System: 3,3a-dihydropyrrolo[1,2-a]quinoxaline-1,4(2H,5H)-dione(1501-32-2)

Safety Data

• Hazardous Substances Data: 1501-32-2(Hazardous Substances Data)

Upstream product

• 148012-86-6 N-(2-nitrophenyl)-glutamic acid dimethyl ester 
• 617-65-2 Glutamic acid 
• 1493-27-2 ortho-nitrofluorobenzene 
• 56-86-0 L-glutamic acid 
• 615-36-1 2-bromoaniline 
• 4931-66-2 methyl 5-oxopyrrolidine-2-carboxylate 
• 149-87-1 Pyroglutamic acid 

Relevant articles and documents

Impact of Functional Groups on the Copper-Initiated N-Arylation of 5-Functionalized Pyrrolidin-2-ones and Their Vinylogues

The electronic effects governing the N-arylation of pyrrolidone were investigated. The generalization of our preliminary findings on a copper(I)-catalyzed Csp2-N coupling process was first improved with a wide variety of aryl and heteroaryl halides and methyl pyroglutamate. The optimized protocol was further extended to pyrrolidin-2-ones substituted at the C5-position with an aryl group bearing an electron-donating or electron-withdrawing group as well as to some of their substituted enaminoester vinylogues. The impact of substituents at the N- and C5-position on these coupling processes seemed to be pivotal for determining both the reaction profiles and yields.

Imidazo[1,5-A]quinoxalines

An invention relating to Imidazo[1,5-a]quinoxalines (I) STR1 which do not contain an endocyclic carbonyl group and which are useful as anxiolytic and sedative/hypnotic agents.