150107-64-5Relevant academic research and scientific papers
γ-turn peptidomimetics as fibrinogen antagonists
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, (2008/06/13)
This invention relates to a method of inhibiting platelet aggregation, and compounds which are mimics of the peptide sequence Arg-Gly-Asp.
The use of γ-turn mimetics to define peptide secondary structure
Callahan,Newlander,Burgess,Eggleston,Nichols,Wong,Huffman
, p. 3479 - 3488 (2007/10/02)
A novel γ-turn mimetic 2 has been prepared based on retro amide peptide design. Incorporation of this mimetic into linear peptide fibrinogen receptor antagonist 7 (GPIIb/IIIa receptor) affords the opportunity to test models of antagonist pharmacophore.
