15017-21-7

Usage

InChI:InChI=1/C18H14N2O2/c21-17-11-10-13-6-4-5-9-15(13)16(17)12-19-20-18(22)14-7-2-1-3-8-14/h1-12,19H,(H,20,22)

Upstream product

• 613-94-5 benzoic acid hydrazide 
• 708-06-5 2-hydroxynaphthalene-1-carbaldehyde 
• 553-53-7 Nicotinic acid hydrazide 
• 93-58-3 benzoic acid methyl ester 

Downstream Products

• 92881-68-0 (OC₁₀H₆CHNNHCOC₆H₅)2U(OOCCH₃)2 
• 1242283-05-1 dimethyl 2-[1-benzoyl-2-({2-[(E)-1,4-dimethoxy-1,4-dioxobut-2-en-2-yloxy]naphthalen-1-yl}methylene)hydrazinyl]fumarate 

Relevant academic research and scientific papers

A highly selective colorimetric and fluorescent chemosensor for Al(III) based-on simple naphthol in aqueous solution

A colorimetric and fluorescent chemosensor (L) for Al(III) was synthesized and fully characterized. L could be both used as a colorimetric and fluorescent chemosensor for the detection of Al3 + ions with low detection limit (8.87 × 10- 7/

Characterization of an Al3+-selective fluorescent probe based on a benzoyl hydrazine derivative and its application in cell imaging

A fluorescent probe based on benzoyl hydrazine was synthesized and characterized as an Al3+-selective fluorescent probe. This probe showed good selectivity towards Al3+ compared to other common ions. Under optimized experimental cond

Antimicrobial activity of aroylhydrazone-based oxido vanadium(v) complexes: In vitro and in silico studies

A tridentate Schiff base ligand (E)-N′-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide (H2L) and its oxido-vanadium(v) complexes with formulae [VO(L)(MeOH)(OMe)] (1), [VO(L)(OEt)] (2), and [VO(L)(OPr)] (3) have been synthesized and fully ch

Structure and biological properties of five Pt(II) complexes as potential anticancer agents

We synthesized and validated five Schiff base Pt(II) complexes derived from 2-hydroxy-1-naphthaldehyde benzoyl hydrazone and its derivatives, which are modified at the benzohydrazide structures (L1–L5). The complexes were [Pt(L1)(DMSO)Cl] (C1), [Pt(L2)(DM

Acylhydrazone Subunits as a Proton Cargo Delivery System in 7-Hydroxyquinoline

The reimagined concept of long-range tautomeric proton transfer using crane subunits is shown by designing and synthesising two new acylhydrazones containing a 7-hydroxyquinoline (7-OHQ) platform. The acylhydrazone subunits attached to the 7-OHQ at the 8t

Multifunctional fluorescence sensor as a potential theranostic agent against Alzheimer's disease

Metal ions play an important role in the pathogenesis of Alzheimer's disease (AD). Metal dyshomeostasis, β-amyloid (Aβ) accumulation and oxidative stress, etc. are related to metal ions. So, metal therapeutics has aroused increasingly more attention, espe

Dioxido-vanadium(V) complex catalyzed oxidation of alcohols and tandem synthesis of oximes: a simple catalytic protocol for C–N bond formation

We report the synthesis of a vanadium(V) complex characterized by FT-IR and 1H NMR spectroscopy. The structure of the complex was established by single crystal X-ray crystallography. We also carried out the catalytic oxidation of benzyl alcohol, hetero-aryl alcohols and propargylic alcohols. Tandem synthesis of oximes from alcohols were also carried out using our vanadium(V) complex. The newly synthesized complex acts as a catalyst for oxidation reactions and tandem synthesis of oxime from alcohols.

Synthesis and X-ray crystal structures of three new nickel(II) complexes of benzoylhydrazones: Catalytic applications in the synthesis of 2-arylbenzoxazoles

Three new complexes of nickel(II), having general formula [Ni(L1)(PPh3)] (1), [Ni(L1)(4-picoline)] (2), and [Ni(L2)(4-picoline)] (3) were synthesized by the reaction of Ni(OAc)2·4H2O with corresponding benzolyhydrazine-derived Schiff base ligands i.e. [4-(diethylamino)-2-hydroxybenzylidene]-benzohydrazonic acid (H2L1) or [2-(hydroxynaphthalen-1-yl)methylene]-benzohydrazonic acid (H2L2) and PPh3/4-picoline as co-ligand in 1:1:1 ratio in methanol. All the three complexes were air-stable, isolated as reddish brown solids and characterized by Elemental analysis, FT-IR, 1H, 13C{1H}, 31P{1H} NMR spectroscopy and mass spectrometry. The structures of all three complexes were determined by single crystal X-ray diffraction studies which revealed the distorted square planar geometry of the complexes. In these complexes, three coordination sites were occupied by ONO pincer type Schiff base ligand and the fourth site was blocked by phosphorus (P) or nitrogen (N) atom of the co-ligand. The catalytic potential of all three complexes was explored in the synthesis of a series of 2-arylbenzoxazoles from aldehydes and 2-aminophenol, using low catalyst loading (0.5 mol%). Complex 1 was found to be the best catalyst among three complexes, for the synthesis of a series of 2-aryl benzoxazoles. The ease of synthesis, air-stability and robustness of the catalyst, and good TONs are some of the key characteristics of the described catalytic system.

BF3-Etherate-catalyzed tandem reaction of 2-formylarylketones with electron-rich arenes/heteroarenes: An assembly of isobenzofurans

An efficient and BF3·Et2O-catalyzed chemoselective synthesis of diversified 1,3-diarylisobenzofuran in a high yield has been described. The reaction proceeds through sequential hydroarylation-cyclization between 2-formylarylketones and electron-rich arenes/heteroarenes. Advantageous features of the developed methodology include operational simplicity, a broad substrate scope, and applicability towards gram scale synthesis. The utility of isobenzofuran derivatives as the diene was extended to the synthesis of [4+2] cyclo-adducts with DMAD and the synthesis of 1,2-dicarbonylarenes in good yields.

Harnessing the reactivity of Ortho-formyl-arylketones: Base-promoted regiospecific synthesis of functionalized isoquinolines

An efficient and base-mediated one-pot regiospecific synthesis of structurally diversified isoquinolines and benzo[h] isoquinolines from easily accessible ortho-formyl-arylketones and aryl/(het)arylmethanamines has been described. Challenging 3-alkynyl/alkenyl isoquinolines and bis-isoquinolines were easily attained through this developed chemistry, which can be further used for various organic transformations. Operational simplicity, high atom-economy, broad substrate scope, functional group tolerance and applicability towards large scale synthesis are the advantageous features of this developed methodology.