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150215-30-8

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150215-30-8 Usage

General Description

1,2,4-Thiadiazole-3-acetic acid, 5-[(ethoxycarbonyl)aMino]- is a chemical compound that belongs to the class of organic compounds known as 1,2,4-thiadiazole-3-acetic acids. It is a derivative of thiadiazole and acetic acid, and its molecular structure consists of a thiadiazole ring with a carboxylic acid group at position 3 and an ethoxycarbonylamino group at position 5. 1,2,4-Thiadiazole-3-acetic acid, 5-[(ethoxycarbonyl)aMino]- has potential applications in the fields of pharmaceuticals and agrochemicals, where it may be utilized as a building block for the synthesis of various biologically active molecules. Its unique structure and properties make it a valuable intermediate for the development of novel compounds with diverse biological activities.

Check Digit Verification of cas no

The CAS Registry Mumber 150215-30-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,2,1 and 5 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 150215-30:
(8*1)+(7*5)+(6*0)+(5*2)+(4*1)+(3*5)+(2*3)+(1*0)=78
78 % 10 = 8
So 150215-30-8 is a valid CAS Registry Number.

150215-30-8Relevant articles and documents

7-acylamino-3-heteroarylthio-3-cephem carboxylic acid antibiotics and prodrugs thereof

-

, (2008/06/13)

The present invention relates to a cephem prodrug having formula III or formula IV: or a pharmaceutically acceptable salt thereof, wherein R′1is selected from the group consisting of hydrogen and —C(O)CH(NH2)CH3and R′2is selected from the group consisting of hydrogen and an acyl group that is cleaved by an enzyme found in mammals, with the proviso that, when either R′1or R′2is hydrogen, the other is not. A, B, L, G, E, and J are each independently nitrogen or carbon such that the respective rings are selected from the group consisting of provided that the group —CH2—S—CH2CH2NHR′2is attached only to a carbon atom of said heterocyclic group, and Q is selected from the group consisting of nitrogen and —CX, wherein X is selected from the group consisting of hydrogen and chlorine.

Practical preparation of (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetic acid: A side-chain of the fourth generation of cephem antibiotics

Tatsuta,Miura,Gunji,Tamai,Yoshida,Inagaki,Kurita

, p. 1701 - 1707 (2007/10/02)

A Z-isomer (4) of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid, which is the common acyl moiety of clinically useful cephem antibiotics, has been prepared from the aminoisoxazoles through the skeletal rearrangement in several routes. Reaction of 3-amino-5-methoxyisoxazole (7) with alkoxycarbonyl isothiocyanates gave methyl 2-(5-alkoxycarbonylamino-1,2,4-thiadiazol-3-yl)acetates (8), which were converted into the target compound 4 through the reaction of the corresponding keto ester with O-methylhydroxylamime. Compound 4 was prepared similarly from 3-aminoisoxazole (10). Also, O-methylation of 2-hydroxyimino-2-(5-methoxycarbonylamino-1,2,4-thiazol-3-yl)acetate (15) with methyl iodide or dimethyl sulfate in the presence of barium oxide and barium hydroxide octahydrate was found to afford exclusively the desired Z-isomer (14a) of methyl 2-(5-methoxycarbonylamino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)aceta te, which was led to 4.

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