150258-63-2

Basic information

• Product Name: TRANS-1-(3'-CARBOXY-4'-HYDROXYPHENYL)-2-(2,5-DIHYDROXYPHENYL)ETHENE
• Synonyms: 5-[2-(2,5-dihydroxyphenyl)ethenyl]-2-hydroxybenzoicacid;5-[(E)-2-(2,5-Dihydroxyphenyl)ethenyl]-2-hydroxybenzoic acid, 3-Carboxy-2',4,5'-trihydroxy-trans-stilbene;5-[(E)-2-(2,5-Dihydroxyphenyl)vinyl]-2-hydroxybenzoic acid
• CAS NO: 150258-63-2
• Molecular Formula: C15H12O5
• Molecular Weight: 272.25278
• Product Categories: Inhibitors;Tyrosine Kinase Inhibitors
• Mol File: 150258-63-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 221-223°C dec.
• Boiling Point: 563.9 °C at 760 mmHg
• Flash Point: 308.9 °C
• Appearance: /
• Density: 1.508 g/cm³
• Storage Temp.: Amber Vial, -20?C Freezer, Under Inert Atmosphere
• PKA: 3.09±0.10(Predicted)
• CAS DataBase Reference: TRANS-1-(3'-CARBOXY-4'-HYDROXYPHENYL)-2-(2,5-DIHYDROXYPHENYL)ETHENE(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-1-(3'-CARBOXY-4'-HYDROXYPHENYL)-2-(2,5-DIHYDROXYPHENYL)ETHENE(150258-63-2)
• EPA Substance Registry System: TRANS-1-(3'-CARBOXY-4'-HYDROXYPHENYL)-2-(2,5-DIHYDROXYPHENYL)ETHENE(150258-63-2)

Safety Data

• Hazardous Substances Data: 150258-63-2(Hazardous Substances Data)

Usage

Description

TRANS-1-(3'-CARBOXY-4'-HYDROXYPHENYL)-2-(2,5-DIHYDROXYPHENYL)ETHENE is a chemical compound characterized by its beige solid appearance. It is a derivative of hydrolyzable tannins, which are naturally occurring polyphenolic compounds found in various plant sources. TRANS-1-(3'-CARBOXY-4'-HYDROXYPHENYL)-2-(2,5-DIHYDROXYPHENYL)ETHENE possesses unique chemical properties, including hydroxy and carboxy groups, that enable interactions with biopolymers and macromolecules, making it a promising candidate for various applications in different industries.

Uses

Used in Pharmaceutical Industry:
TRANS-1-(3'-CARBOXY-4'-HYDROXYPHENYL)-2-(2,5-DIHYDROXYPHENYL)ETHENE is used as a novel tyrosine kinase inhibitor for its extremely high potency against immunoprecipitated p56lck (IC50 = 60nM). This application is significant in the development of targeted therapies for various diseases, including cancer, as tyrosine kinases play a crucial role in cell signaling and regulation.
Used in Chemical Research:
As a compound with unique chemical properties, TRANS-1-(3'-CARBOXY-4'-HYDROXYPHENYL)-2-(2,5-DIHYDROXYPHENYL)ETHENE can be utilized in chemical research for the development of new drugs, materials, and technologies. Its hydroxy and carboxy groups allow for further modification and functionalization, making it a versatile building block in the synthesis of more complex molecules.
Used in Material Science:
The compound's ability to interact with biopolymers and macromolecules suggests potential applications in material science, where it could be used to develop novel materials with enhanced properties, such as improved mechanical strength, thermal stability, or biocompatibility.