Cas 150283-03-7,(R)-5-[(1S,3R,9S,10R,13R,14R,17R)-1,3-Bis-(tert-butyl-dimethyl-silanyloxy)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2,2-difluoro-3-hydroxy-hexanoic acid ethyl ester

150283-03-7

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Basic information

Product Name: (R)-5-[(1S,3R,9S,10R,13R,14R,17R)-1,3-Bis-(tert-butyl-dimethyl-silanyloxy)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2,2-difluoro-3-hydroxy-hexanoic acid ethyl ester
Synonyms: (R)-5-[(1S,3R,9S,10R,13R,14R,17R)-1,3-Bis-(tert-butyl-dimethyl-silanyloxy)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2,2-difluoro-3-hydroxy-hexanoic acid ethyl ester
CAS NO:150283-03-7
Molecular Formula:
Molecular Weight: 711.134
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (R)-5-[(1S,3R,9S,10R,13R,14R,17R)-1,3-Bis-(tert-butyl-dimethyl-silanyloxy)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2,2-difluoro-3-hydroxy-hexanoic acid ethyl ester(CAS DataBase Reference)
NIST Chemistry Reference: (R)-5-[(1S,3R,9S,10R,13R,14R,17R)-1,3-Bis-(tert-butyl-dimethyl-silanyloxy)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2,2-difluoro-3-hydroxy-hexanoic acid ethyl ester(150283-03-7)
EPA Substance Registry System: (R)-5-[(1S,3R,9S,10R,13R,14R,17R)-1,3-Bis-(tert-butyl-dimethyl-silanyloxy)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2,2-difluoro-3-hydroxy-hexanoic acid ethyl ester(150283-03-7)

Safety Data

Hazard Codes: N/A
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Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 150283-03-7(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 150283-03-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,2,8 and 3 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 150283-03:
(8*1)+(7*5)+(6*0)+(5*2)+(4*8)+(3*3)+(2*0)+(1*3)=97
97 % 10 = 7
So 150283-03-7 is a valid CAS Registry Number.

150283-03-7Upstream product

20998-18-9 1α,3β-dihydroxy-androst-5-en-17-one

150283-03-7Downstream Products

72696-49-2 24F₂-1,25(OH)2-D₃

150283-03-7Relevant academic research and scientific papers

An alternative and efficient synthesis of 24,24-difluoro-1α,25-dihydroxyvitamin D3

Konno,Ojima,Hayashi,Takayama

, p. 1120 - 1124 (2007/10/02)

An alternative synthesis of the title compound 2, a highly potent analog of 1α,25-dihydroxyvitamin D3 (1), is described. Starting with 1α,3β-bis[(tert-butyldimethylsilyl)oxy]androst-5-ene (8), 2 was obtained in 3.8% total yield through 10 steps. This method provides compound 2 in much higher yield than that reported previously.

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