150331-80-9

Upstream product

• 146255-30-3 2(S)-azido-2-(3(R)-tetrahydrofuranyl)acetic acid 
• 136522-17-3 cis-N-butyldecahydro-2-<2(R)-hydroxy-4-phenyl-3(S)-aminobutyl>-(4aS,8aS)-isoquinoline-3(S)-carboxamide 
• 42238-15-3 (2E)-4-phenylbut-2-en-1-ol 
• 78571-81-0 (R,R)-3-(phenylmethyl)oxiranemethanol 
• 128019-40-9 (3S,4aS,8aS)-N-tert-butyl-decahydroisoquinoline-3-carboxamide 
• 136465-90-2 N-tert-butyl-2-<2(R)-hydroxy-4-phenyl-3(S)-azidobutyl>decahydro(4aS,8aS)-isoquinoline-3(S)-carboxamide 
• 146255-29-0 3-(2-(2(S)-azido-3(R)-tetrahydrofuranyl)-1-oxoethyl)-4(S)-(phenylmethyl)-2-oxazolidinone 
• 146255-27-8 3-(2-(3(R)-tetrahydrofuranyl)-1-oxoethyl)-4(S)-(phenylmethyl)-2-oxazolidinone 
• 146255-22-3 diethyl (3(R)-tetrahydrofuranyl)malonate 
• 1354951-08-8 (R)-2-(Tetrahydro-furan-3-yl)-malonic acid 
• 146255-25-6 (2(R)-tetrahydrofuranyl)acetic acid 
• 136465-89-9 (2S)-2-[1'(S)-1-azido-2-phenylethyl]oxirane 
• 116949-67-8 (2S,3S)-2-azido-1-phenyl-butane-3,4-diol 

Downstream Products

• 150331-81-0 N-tert-butyl-2-<2(R)-hydroxy-4-phenyl-3(S)-((2(S)-amino-2-3(R)-tetrahydrofuranyl)acetyl)butyl>decahydro-(4aS,8aS)-isoquinoline-3(S)-carboxamide 

Relevant academic research and scientific papers

Potent HIV Protease Inhibitors: The Development of Tetrahydrofuranylglycines as Novel P2 Ligands and Pyrazine Amides as P3-Ligands

A series of protease inhibitors bearing constrained unnaturel amino acids at the P2-position and novel heterocycles at the P3-position of compound 1 (Ro 31-8959) were synthesized, and their in vitro enzyme inhibitory and antiviral ac