150334-50-2Relevant academic research and scientific papers
The first highly asymmetric pummerertype reaction in chiral acyclic sulfoxides: Chemistry of O-silylated ketene acetals
Kita, Yasuyuki,Shibata, Norio,Yoshida, Naoki
, p. 4063 - 4066 (1993)
The chiral sulfoxides (4) were reacted with O-silylated ketene acetal (2) in acetonitrile to give the corresponding α-siloxysulfides (5) in high degree of stereochemistry and high yields.
First Highly Asymmetric Pummerer-type Reaction in Chiral, Non-racemic Acyclic Sulfoxides Induced by O-Silylated Ketene Acetal
Kita, Yasuyuki,Shibata, Norio,Yoshida, Naoki,Fujita, Shigekazu
, p. 3335 - 3342 (2007/10/02)
Various types of syn- and anti-β-substituted sulfoxides 6b-e, g reacted with ketene tert-butyldimethylsilyl acetal 2 in the presence of a catalytic amount of zinc iodide in acetonitrile to give high yields of the corresponding α-siloxy sulfides 7b-e, g stereoselectively.Similarly, chiral, non-racemic sulfoxides 6a, f, h, i reacted with acetal 2 in acetonitrile to give the chiral, non-racemic α-siloxy sulfides 7a, f, h, i in high yields.
