150352-17-3

Basic information

• Product Name: 4H-Indazol-4-one, 1,5,6,7-tetrahydro-6,6-dimethyl-
• Synonyms: 4H-Indazol-4-one, 1,5,6,7-tetrahydro-6,6-dimethyl-
• CAS NO: 150352-17-3
• Molecular Weight: 164.207
• Mol File: 150352-17-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 4H-Indazol-4-one, 1,5,6,7-tetrahydro-6,6-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Indazol-4-one, 1,5,6,7-tetrahydro-6,6-dimethyl-(150352-17-3)
• EPA Substance Registry System: 4H-Indazol-4-one, 1,5,6,7-tetrahydro-6,6-dimethyl-(150352-17-3)

Safety Data

• Hazardous Substances Data: 150352-17-3(Hazardous Substances Data)

Usage

Chemical compound

4H-Indazol-4-one, 1,5,6,7-tetrahydro-6,6-dimethyl-

Derivative

4H-indazole with tetrahydro-6,6-dimethylsubstituent at positions 1, 5, 6, and 7

Potential applications

pharmaceuticals, medicinal chemistry

Biological activities and therapeutic properties

may exhibit these properties
Candidate for further research and development in drug discovery and design

Upstream product

• 75039-59-7 2-dimethylaminomethylene-5,5-dimethylcyclohexane-1,3-dione 
• 126-81-8 dimedone 

Downstream Products

• 596845-57-7 6,6-dimethyl-2-trityl-2,5,6,7-tetrahydro-indazol-4-one 
• 1355248-93-9 C₁₇H₁₉BrN₂O₂ 
• 1355248-91-7 C₁₇H₂₀N₂O₂ 
• 1355248-92-8 C₁₇H₂₀N₂O₂ 

Relevant articles and documents

A Novel Amino Protection-Deprotection Procedure and Its Application in Solid Phase Peptide Synthesis

N-4,4-Dimethyl-2,6-dioxocyclohexylidenemethyl (Dcm) amino acids are readily prepared and the protecting group can be removed with hydrazine at room temperature; their potential in solid phase peptide synthesis is illustrated.

Novel crown ether functionalized imidazolium-based acidic ionic liquid catalyzed synthesis of pyrazole derivatives under solvent-free conditions

Abstract An innovatively designed novel crown ether functionalized imidazolium-based reusable acidic ionic liquid [crown ether MIm] [HSO4] has been efficiently implemented for the synthesis of pyrazole derivatives using various substituted enaminones, hydrazine hydrate and phenyl hydrazine under solvent-free conditions. Structural novelty and task efficiency of the catalyst, high yields of desired products, greener approach attributing high atom economy and solvent-free conditions render this protocol suitable to cope with the current demand in contemporary organic chemistry. The inventive idea of utilizing crown ether functionalized ionic liquid as a catalyst was for the first time demonstrated in this protocol.

TRICYCLIC COMPOUNDS AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS

The present invention describes and claims compounds of the Structural Formula I, Structural Formula II, or Structural Formula III: wherein R1, R2, R3 and R3' are -H or methyl, or R3 and R3 taken together form a double bond, or R3' is -H and R2 and R3 taken together form a spiro-cyclopropyl substituent, R4 is -H or -F, and R5 is -H, methyl, -CI or -Br, Formula II wherein R1 is -H, ethyl-, isopropyl-, cyclopropyl-, methyl- or methoxy-, R4 is -H or -F, and "Y" is: (a) -CH2-; (b) -CR6H-0-CR7R8-, wherein R6, R7, and R8 are independently - H or methyl; (c) -CR6H-N(R9)-CR7R8-, wherein R6, R7, and R8 are independently -H or methyl; (d) -CH2-C(R9)(R10)-C(R7)(R8)-, wherein R7, R8, R9 and R10 are independently - H or -methyl, or both R7 and R8 are -F, R9 and R10 are independently -H or -methyl, or both R9 and R10 are -F, or R9 and R10 taken together are (0=), which together with the carbon to which they are attached forms a carbonyl group.